Add to ORKGDEAD-box proteins comprise a family of ATP-dependent RNA helicases involved in several aspects of RNA metabolism. Here we report the characterization of the human DEAD-box RNA helicase DDX26. The gene is composed of 14 exons distributed over an extension of 8,123 bp of genomic sequence and encodes a transcript of 1.8 kb that is expressed in all tissues evaluated. The predicted amino acid sequence shows a high similarity to a yeast DEAD-box RNA helicase (Dbp9b) involved in ribosome biogenesis. The new helicase maps to 7p12, a region of frequent chromosome amplifications in glioblastomas involving the epidermal growth factor receptor (EGFR) gene. Nevertheless, co-amplification of DDX26 with EGFR was not detected in nine tumors analyzed
International audienceThe DEAD/DEAH box RNA helicases are a superfamily of proteins involved in the ...
A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to human
RNA helicases are enzymes that bind or remodel RNA and RNA-protein complexes. They are involved in n...
DEAD-box RNA helicases play various, often critical, roles in all processes where RNAs are involved....
Nucleic acid helicases are characterized by the presence of the helicase domain containing eight mot...
Gene expression in eukaryotes is highly complex. The central player in gene expression is the messen...
DEAD-box RNA helicases are important regulators of RNA metabolism and have been implicated in the de...
The p68 protein is immunologically related to large T antigen, the dominant transforming oncogene of...
The human DEAD/H-box RNA helicase DDX6 (RCK/p54) is a protein encoded by the fusion gene from the t(...
The mammalian DEAD-box RNA helicase DDX5, its paralog DDX17, and their orthologs in Saccharomyces ce...
Ester Cannizzaro ROLE OF DDX RNA HELICASES IN CANCER CELLS Abstract DEAD-BOX (DDX) RNA helicases...
The human p68 protein, an SV40 large T related antigen, is an RNA dependent ATPase and RNA helicase....
P72, a novel human member of the DEAD box family of putative RNA-dependent ATPases and ATP-dependent...
RNA helicases of the DEAD-box family are involved in several metabolic pathways, from transcription ...
Members of the DEAD box family of RNA helicases, which are characterised by the presence of twelve c...
International audienceThe DEAD/DEAH box RNA helicases are a superfamily of proteins involved in the ...
A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to human
RNA helicases are enzymes that bind or remodel RNA and RNA-protein complexes. They are involved in n...
DEAD-box RNA helicases play various, often critical, roles in all processes where RNAs are involved....
Nucleic acid helicases are characterized by the presence of the helicase domain containing eight mot...
Gene expression in eukaryotes is highly complex. The central player in gene expression is the messen...
DEAD-box RNA helicases are important regulators of RNA metabolism and have been implicated in the de...
The p68 protein is immunologically related to large T antigen, the dominant transforming oncogene of...
The human DEAD/H-box RNA helicase DDX6 (RCK/p54) is a protein encoded by the fusion gene from the t(...
The mammalian DEAD-box RNA helicase DDX5, its paralog DDX17, and their orthologs in Saccharomyces ce...
Ester Cannizzaro ROLE OF DDX RNA HELICASES IN CANCER CELLS Abstract DEAD-BOX (DDX) RNA helicases...
The human p68 protein, an SV40 large T related antigen, is an RNA dependent ATPase and RNA helicase....
P72, a novel human member of the DEAD box family of putative RNA-dependent ATPases and ATP-dependent...
RNA helicases of the DEAD-box family are involved in several metabolic pathways, from transcription ...
Members of the DEAD box family of RNA helicases, which are characterised by the presence of twelve c...
International audienceThe DEAD/DEAH box RNA helicases are a superfamily of proteins involved in the ...
A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to human
RNA helicases are enzymes that bind or remodel RNA and RNA-protein complexes. They are involved in n...