Colateral effects of local anesthesia with vasoconstritors in bovine

In order to study the effects of different local anaesthetics with and without vasoconstritor (epinefrine), 20 adult crossbred cows were used. The following treatments were carried out:T1 - control (bidistilled water); T2 - chloridrate of lidocaine (20 mg/ml) with epinephrine (0.005 mg/ml); T3 - chloridrate of lidocaine (20 mg/ml) with epinephrine (0.02 mg/ml); T4 - chloridrate of lidocaine (20 mg/ml) with epinephrine (0.05 mg/ml); T5 - chloridrate of lidocaine(20 mg/ml); T6 - chloridrate of procaine (22 mg/ml) with epinefrine (0.02 mg/ml); T7 - chloridrate of procaine (22 mg/ml). The different solutions were injected, at the same time, into the subcutaneous space of the medial chest line, 10cm apart, of all cows. Observation at the infiltration sites was made 72 hours later, for the presence or not of tissue reaction, as well as lesion degrees. No differences were found among T1, T5, T6, and T7 , which did not cause tissue reaction. On the other hand, lower lesion tissue degrees were found in cows treated with T2 as compared to T3 and T4. It can be concluded that the use of both local anaesthetics alone or chloridrate of procaine with epinefrine are harmless to the skin while chloridrate of lidocaine associated with any concentration of vasoconstritor may give rise to tissue lesions in cattle