Galectins are a family of evolutionarily conserved animal lectins, widely distributed from lower invertebrates to mammals. They share sequence and structure similarities in the carbohydrate recognition domain and specificity for polylactosamine-enriched glycoconjugates. In the last few years significant experimental data have been accumulated concerning their participation in different biological processes requiring carbohydrate recognition such as cell adhesion, cell growth regulation, inflammation, immunomodulation, apoptosis and metastasis. In the present review we will discuss some exciting questions and advances in galectin research, highlighting the significance of these proteins in immunological processes and their implications in bi...
Recent evidence has implicated galectins, a family of evolutionarily conserved carbohydrate-binding ...
The immune system has evolved sophisticated mechanisms composed of several checkpoints and fail-safe...
Recent evidence has implicated galectins and their ligands as master regulators of immune cell homeo...
Galectins are a family of evolutionarily conserved animal lectins, widely distributed from lower inv...
Over the last decade, we have witnessed an explosion of information regarding the function of glycoc...
Inflammation is a critical process for eliminating pathogens, but can lead to serious deleterious ef...
Galectins are beta-galactoside binding mammalian lectins and they share homologous carbohydrate reco...
Inflammation involves the sequential activation of signalling pathways leading to the production of ...
B-galactoside-binding animal lectins, are differentially expressed by various immune cells, as well ...
Galectins are carbohydrate-binding proteins that are involved in many physiological functions, such ...
A family of β-galactosides-binding proteins, called galectins, have recently emerged as novel molecu...
In the post-genomic era, many efforts have been devoted to better understanding the biological infor...
Galectins are a family of animal lectins that bind beta-galactosides. Outside the cell, galectins bi...
Galectins are a family of ancient animal carbohydrate binding proteins; the name is from their descr...
Protein-glycan interactions control essential immunological processes, including T-cell activation, ...
Recent evidence has implicated galectins, a family of evolutionarily conserved carbohydrate-binding ...
The immune system has evolved sophisticated mechanisms composed of several checkpoints and fail-safe...
Recent evidence has implicated galectins and their ligands as master regulators of immune cell homeo...
Galectins are a family of evolutionarily conserved animal lectins, widely distributed from lower inv...
Over the last decade, we have witnessed an explosion of information regarding the function of glycoc...
Inflammation is a critical process for eliminating pathogens, but can lead to serious deleterious ef...
Galectins are beta-galactoside binding mammalian lectins and they share homologous carbohydrate reco...
Inflammation involves the sequential activation of signalling pathways leading to the production of ...
B-galactoside-binding animal lectins, are differentially expressed by various immune cells, as well ...
Galectins are carbohydrate-binding proteins that are involved in many physiological functions, such ...
A family of β-galactosides-binding proteins, called galectins, have recently emerged as novel molecu...
In the post-genomic era, many efforts have been devoted to better understanding the biological infor...
Galectins are a family of animal lectins that bind beta-galactosides. Outside the cell, galectins bi...
Galectins are a family of ancient animal carbohydrate binding proteins; the name is from their descr...
Protein-glycan interactions control essential immunological processes, including T-cell activation, ...
Recent evidence has implicated galectins, a family of evolutionarily conserved carbohydrate-binding ...
The immune system has evolved sophisticated mechanisms composed of several checkpoints and fail-safe...
Recent evidence has implicated galectins and their ligands as master regulators of immune cell homeo...