Characteristics of clinical signs of migraine in children

CILJ ISTRAŽIVANJA: Cilj ovog istraživanja bio je odrediti osobitosti kliničke simptomatologije migrene u dječjoj dobi te lokalizaciju i vrijeme javljanja migrenskih glavobolja. Također, jedan od ciljeva bio je odrediti fenomene pridružene migreni i njihovu učestalost. USTROJ STUDIJE: Studija je ustrojena kao retrospektivna presječna studija. ISPITANICI I METODE: Studijom je obuhvaćeno 51 dijete s migrenom pregledano u periodu od 2012.-2017. godine na Odjelu za pedijatriju u Općoj županijskoj bolnici Požega. U istraživanju se koristila medicinska dokumentacija iz koje su analizirani podatci o dobi, spolu, osobitosti kliničke slike, terapije, EEG-a, MR mozga, TCD i učestalosti napadaja. Podatci su obrađeni statističkim programom MedCalc Statistical Software version 17.8.2. REZULTATI: Središnja vrijednost dobi ispitanika s migrenom iznosi 13 godina u rasponu od 6 do 17 godina, a oba su spola podjednako obolijevala. Glavobolja je najčešće bila pulsirajućeg karaktera i locirana difuzno. Migrena se javljala danju u 76,5 % ispitanika. Djeca mlađa od 13 godina češće su uz migrenu povraćala, a od ostalih fenomena najčešće su se javljali fotofobija (31,4 %) i vidni simptomi (27,5 %). Medijan napadaja u jednom mjesecu iznosi 2, a ženska djeca imaju značajno veći broj napadaja. ZAKLJUČAK: Migrene se učestalije javljaju u djece starije od 10 godina te podjednako u obama spolovima. Glavobolja je locirana difuzno i pulsirajućeg je tipa, a uz glavobolju najčešći je simptom povraćanje. Migrenozni se napadaji u prosjeku javljaju 2 puta mjesečno, no mnogo češće u ženskog spola. napadaji su učestaliji danju, a ispitanice ženskoga spola češće se bude noću.OBJECTIVE: The aim of this study was to determine the characteristics of clinical symptoms of migraine in children as well as the localization and time of appearance. Furthermore, the aim was to determine the associated migraine phenomena and their frequency. STUDY DESIGN: The study is structured as a retrospective cross-sectional study. PARTICIPANTS AND METHODS: The study included 51 children with migraine, examined from 2012 to 2017 at the Department of Pediatrics at Požega General Hospital. The data analyzed were taken from the medical records including: age, gender, clinical status, therapy, EEG, brain MRI, TCD, and frequency. The data were processed in the statistical program MedCalc Statistical Software version 17.8.2. RESULTS: The mean age of subjects with migraine is 13 ranging from 6 to 17, with both sexes approximately equally represented. The headache was usually pulsating and located diffusely. In 76.5% subjects migraine attack happened during the day. Children under the age of 13 more frequently vomited, and other most common phenomena were photophobia (31.4%) and visual symptoms (27.5%). Median of the attacks in one month is 2, while female children have significantly more frequent attacks. CONCLUSION: Migraines occur more frequently in children older than 10 years of age, and in both sexes. The headache is located diffusely and has a pulsating character. Vomiting is the most common symptom associated with the headache. Migraine attacks occur on average twice a month, but more frequently in females. Attacks are more frequent during the daytime, and female subjects are more likely to have an attack which wakes them up during the night