Pathogenic bacteria - mechanisms of causing infections

Bakterije moraju savladati više prepreka kako bi se postigla uspješna patogenost. U mnogim slučajevima, to zahtijeva zaobilaženje prve linije obrane domaćina: epitelne površine koja nam pruža zaštitnu barijeru za probavni, dišni i mokraćni put. Za svladavanje tih prepreka, patogeni mikroorganizmi cesto pokreću mehanizme koji iskorištavaju važne stanične procese epitela. Ovi stanični procesi su od ključne važnosti za naše razumijevanje bakterijske patogenosti.Bacteria must overcome multiple obstacles in order to achieve successful pathogenesis. In many cases, this requires bypassing the first line of host defense: the barrier provided by epithelial surfaces of the integument and the gastrointestinal, respiratory and urinary tracts. To overcome these barriers, pathogenic organisms frequently initiate mechanisms that exploit essential cellular processes of the epithelium. These cellular processes are therefore critical to our understanding of bacterial pathogenesis