The frequency of perioperative myocardial infarction in patients operated on a beating heart

Cilj istraţivanja: Glavni cilj ovog istraţivanja bio je odrediti uĉestalost perioperativnog infarkta kod pacijenata koji su bili operirani u Kliniĉkom centru Osijek na Kliniĉkom odijelu za kardijalnu kirurgiju tijekom 2011. i 2012. godine. Nacrt studije: Retrospektivna analiza medicinske dokumentacije. Metode: U ovom znanstvenom radu korišten je srĉani troponin I kao najznaĉajniji pokazatelj infarkta miokarda, koji je najteţi oblik ishemijske bolesti srca i glavni uzrok smrtnosti u razvijenim zemljama. U odreĊivanju pojavnosti perioperativnog infarkta kao granicu razine tropononina I u krvi uzeta je vrijednost od 3,5 μg/L. Kod svih pacijenata koji su sudjelovali u istraţivanju bila je obavljena operacija revaskularizacije miokarda i to na kucajućem srcu. Rezultati: Od istraţivanih 69 pacijenata, kod njih 20 došlo je do perioperativnog infarkta, što ĉini udio od 29 %. Dobiveni rezultati pokazali su kako nema statistiĉki znaĉajne povezanosti izmeĊu perioperativnog infarkta miokarda te hipertenzije, šećerne bolesti, dobi, spola, pretilosti i hiperlipidemije. Korelacijskom analizom utvrĊeno je kako postoji pozitivna niska statistiĉki znaĉajna povezanost izmeĊu pretilosti i hipertenzije (r = 0,26), zatim pretilosti i šećerne bolesti (r = 0,25) te izmeĊu hipertenzije i šećerne bolesti (r = 0,29). Hi-kvadratom testom nisu dobivene statistiĉki znaĉajne razlike izmeĊu riziĉnih ĉimbenika i perioperativnog infarkta miokarda. Zakljuĉak: Najznaĉajniji riziĉni ĉimbenici prouĉavani u ovoj studiji nisu pokazali statistiĉki znaĉajnu povezanost s perioperativnim infarktom miokarda niti statistiĉki znaĉajnu razliku. To moţemo pripisati tome što se radi o relativno maloj te visoko riziĉnoj skupini pacijenata.Objectives: The main objective of this study was to determine the frequency of perioperative myocardial infarction in patients treated at the Clinical department of Cardiac Surgery, Department of Surgery and Neurosurgery of University Hospital Center Osijek, Croatia trough years 2011 and 2012. Study Design: Retrospective analysis of medical records. Methods: Cardiac troponin I was used as the most important indicator for myocardial infarction diagnosis, which is the most severe form of ischemic heart disease, and main cause of mortality in urban countries. As a criteria for diagnosis of perioperative myocardial infarction level of cardiac troponin I higher than 3.5 μg/L was used. All the patients included in this study, were operated for revascularization of a myocardia without the extracorporeal circulation machine. Results: Out of 69 patients included in this study, 20 of them had perioperative myocardial infarction, which makes a quota of 29 %. The results obtained in this study show that there is not statistically significant correlation between perioperative myocardial infarction and hypertension, age, sex, obesity and dyslipidemia. Correlation analysis indicated that there is a statistically significant minor positive correlation between obesity and hypertension (r = 0.26), obesity and diabetes (r = 0.25) and between hypertension and diabetes (r = 0.29). Chi-squared test did not show statistically significant differences between risk factors and perioperative myocardial infarction. Conclusion: The most common risk factors observed in this study did not show a significant correlation with perioperative myocardial infarction. That can be explained with the fact that the studied group was relatively small, and high-risk patients were more prevalent