Development and Evaluation of Multidimensional Gas Chromatographic and Mass Spectrometric Techniques for the Analysis of Highly Complex Chemical Mixtures

For the analysis of highly complex chemical mixtures, new interpretation methods and new techniques were introduced. The data interpretation methods introduced incorporates the unique chemical and physical interactions of compound classes with the stationary phase of a two-dimensional gas chromatographic system and the unique fragmentation pattern observed for different compound classes. Photo ionisation mass spectrometry, which produces mostly molecular ions, were successfully used in new two- and three-dimensional separation techniques