Add to ORKG<p>DNA plasmids encoding Mycobacterium tuberculosis antigen 85 (Ag85) were tested as vaccines in animal models. Ag85 DNA induced relevant immune responses (i.e. T helper (Th) cells, Th1 cytokines and cytotoxic T lymphocytes) and was protective in mouse and guinea pig models of mycobacterial disease. Therefore, DNA vaccination holds promise as an effective means of preventing tuberculosis in humans. Furthermore, this technique is amenable to identifying the protective antigens of M. tuberculosis.</p></p
Cell-mediated immune responses are crucial in the protection against tuberculosis. In this study, we...
Immune response and protective efficacy for the combination of four tuberculosis DNA vaccines were e...
Although most cases of tuberculosis ( TB) can be cured with antibiotics, relapse is common if patien...
<p>Tuberculosis is the most widespread and lethal infectious disease affecting humans. Immuniz...
<p><b>OBJECTIVE: </b>To determine the efficacy of Ag85A-DNA against challenge with...
<p>BALB/c and C57BL/6 mice were injected intramuscularly with plasmid DNA encoding the three c...
DNA vaccine may be a promising tool for controlling tuberculosis development. However, vaccines enco...
<p>Vaccination of mice with plasmid DNA carrying the gene for the major secreted mycobacterial...
Over the last few years, some of our experiments in which mycobacterial antigens were presented to t...
<p>DNA vaccination is an effective means of inducing both humoral and cell-mediated immunity i...
DNA vaccination is an effective method for elicitation of strong humoral as well as cellular immune ...
The development of more effective antituberculosis vaccines would assist in the control of the globa...
Bovine tuberculosis is a major cause of economic loss in countries where it is endemic, and in some ...
Three proteins secreted from Mycobacterium tuberculosis, Ag85B, ESAT-6 and MPT63 were selected as an...
Cell-mediated immune responses are crucial in the protection against tuberculosis. In this study, we...
Cell-mediated immune responses are crucial in the protection against tuberculosis. In this study, we...
Immune response and protective efficacy for the combination of four tuberculosis DNA vaccines were e...
Although most cases of tuberculosis ( TB) can be cured with antibiotics, relapse is common if patien...
<p>Tuberculosis is the most widespread and lethal infectious disease affecting humans. Immuniz...
<p><b>OBJECTIVE: </b>To determine the efficacy of Ag85A-DNA against challenge with...
<p>BALB/c and C57BL/6 mice were injected intramuscularly with plasmid DNA encoding the three c...
DNA vaccine may be a promising tool for controlling tuberculosis development. However, vaccines enco...
<p>Vaccination of mice with plasmid DNA carrying the gene for the major secreted mycobacterial...
Over the last few years, some of our experiments in which mycobacterial antigens were presented to t...
<p>DNA vaccination is an effective means of inducing both humoral and cell-mediated immunity i...
DNA vaccination is an effective method for elicitation of strong humoral as well as cellular immune ...
The development of more effective antituberculosis vaccines would assist in the control of the globa...
Bovine tuberculosis is a major cause of economic loss in countries where it is endemic, and in some ...
Three proteins secreted from Mycobacterium tuberculosis, Ag85B, ESAT-6 and MPT63 were selected as an...
Cell-mediated immune responses are crucial in the protection against tuberculosis. In this study, we...
Cell-mediated immune responses are crucial in the protection against tuberculosis. In this study, we...
Immune response and protective efficacy for the combination of four tuberculosis DNA vaccines were e...
Although most cases of tuberculosis ( TB) can be cured with antibiotics, relapse is common if patien...