Concentration Compounds with Hidrxyquinolin Acid

Hidroksikinolinska kiselina naziv je za 4-hidroksikinolin-2-karboksilnu kiselinu koja nastaje kao metabolit triptofana u organizmu. Mnogi enzimi u svojim aktivnim mjestima sadrže metalne ione, pa se tako i hidroksikinolinska kiselina može kompleksirati s različitim kationima prijelaznih metala. U ovom završnom radu istražene su reakcije hidroksikinolinske kiseline s kationima cinka, kobalta, nikla, bakra, žive i srebra tako što su pripravljene serije otopina hidroksikinolinske kiseline i soli prijelaznih metala u vodi pri odreĎenom pH. Dobiveni su spojevi okarakterizirani infracrvenom spektroskopijom i termogravimetrijskom analizom. Predložene su strukture spojeva na temelju dobivenih rezultata.Hydroxyquinolinic acid is a common term used for 4-hydroxyquinolin-2-carboxylic acid which is a product of normal metabolism of triptophan. Large number of enzymes contain metal ion in their active site, so does hydroxyquinolinic acid which can coordinate with different cations of transition metals. In this thesis reactions of hydroxyquinolinic acid with cations of zinc, cobalt, nickel, copper, mercury and silver have been studied. Series of water solutions of hydroxyquinolinic acid and salts of transition metals were prepared within certain pH value. Synthesized compounds were characterized by infrared spectroscopy and thermogravimetric analysis. As a result, structures of synthesized compounds were proposed