The intestinal tract of all known vertebrate animals is colonized with a high density of bacteria, forming host-specific communities. These communities are usually composed of a broad range of different species that have co-evolved with the host, to form very close and beneficial. In this thesis we developed a new tool for the study of host-microbiota interactions, based on the use of a proliferation controlled commensal E. coli strain and germ-free mice. This strain, contained a severe cell wall synthesis defect leading to the inability of proliferate without external supplementation. To guarantee the tightness of our system and its similarity to the wild type strain, we tested extensively the strain properties even under extreme cell wall...
Most mucosal surfaces of the mammalian body are colonized by microbial communities (‘‘microbiota’’)....
Indigenous microbes inside the host intestine maintain a complex self-regulating community. The mech...
The commensal microbiota protects the murine host from enteric pathogens. Nevertheless, specific pat...
The intestinal tract of all known vertebrate animals is colonized with a high density of bacteria, f...
Intestinal microbiota comprise microbial communities that reside in the gastrointestinal tract and a...
The intestinal ecosystem is formed by a complex, yet highly characteristic microbial community. The ...
The mammalian gut microbiota confers colonization resistance against pathogenic bacteria. Specific p...
The intestinal ecosystem is formed by a complex, yet highly characteristic microbial community. The ...
There is the notion that infection with a virulent intestinal pathogen induces generally stronger mu...
The intestinal ecosystem is formed by a complex, yet highly characteristic microbial community. The ...
Understanding how Salmonella species establish successful infections remains a foremost research pri...
Most Salmonella enterica serovars are believed to have a cyclical lifestyle involving both host-asso...
Intravenous inoculation of Salmonella enterica serovar Typhimurium into mice is a prime experimental...
Salmonella are a diverse group of pathogenic bacteria that remains a serious public health concern w...
Research in the areas of microbiome science and immunology have identified different members of a ho...
Most mucosal surfaces of the mammalian body are colonized by microbial communities (‘‘microbiota’’)....
Indigenous microbes inside the host intestine maintain a complex self-regulating community. The mech...
The commensal microbiota protects the murine host from enteric pathogens. Nevertheless, specific pat...
The intestinal tract of all known vertebrate animals is colonized with a high density of bacteria, f...
Intestinal microbiota comprise microbial communities that reside in the gastrointestinal tract and a...
The intestinal ecosystem is formed by a complex, yet highly characteristic microbial community. The ...
The mammalian gut microbiota confers colonization resistance against pathogenic bacteria. Specific p...
The intestinal ecosystem is formed by a complex, yet highly characteristic microbial community. The ...
There is the notion that infection with a virulent intestinal pathogen induces generally stronger mu...
The intestinal ecosystem is formed by a complex, yet highly characteristic microbial community. The ...
Understanding how Salmonella species establish successful infections remains a foremost research pri...
Most Salmonella enterica serovars are believed to have a cyclical lifestyle involving both host-asso...
Intravenous inoculation of Salmonella enterica serovar Typhimurium into mice is a prime experimental...
Salmonella are a diverse group of pathogenic bacteria that remains a serious public health concern w...
Research in the areas of microbiome science and immunology have identified different members of a ho...
Most mucosal surfaces of the mammalian body are colonized by microbial communities (‘‘microbiota’’)....
Indigenous microbes inside the host intestine maintain a complex self-regulating community. The mech...
The commensal microbiota protects the murine host from enteric pathogens. Nevertheless, specific pat...