We have previously shown that a polymeric (PMMA) chip with medium perfusion and integrated heat regulation provides sufficiently precise heat regulation, pH-control and medium exchange to support cell growth for weeks. However, it was unclear how closely the cells cultured in the chip resembled cells cultured in the culture flask. In the current study, gene expression profiles of cells cultured in the chip were compared with gene expression profiles of cells cultured in culture flasks. The results showed that there were only two genes that were differently expressed in cells grown in the cell culture chip compared to cell culture flasks. The cell culture chip could without further modification support cell growth of two other cell lines. Li...
Artificial animal cell culture was successfully developed by Ross Harrison in 1907. But it was not u...
In vitro microenvironments used for culturing and studying living cells have remained virtually unch...
Microfluidics is emerging as a promising platform for cell culture, enabling increased microenvironm...
In vitro study at the cellular level is an important step in evaluation of biological properties of ...
In this project, the microfludic cell culture chip and array has been designed and fabricated by co...
Cell culture has been a fundamental tool for the study of cell biology, tissue engineering, stem cel...
Lab-on-a-chip systems are promising tools in the field of cell engineering. Microfluidic systems are...
Here we present a microfluidic culture platform for enhancing single stem cell survival. Traditional...
A physiologically relevant environment is essential for successful long-term cell culturing in vitro...
Lab-on-chip systems are microfluidic devices that can be used as powerful tools for research in fiel...
In cell manufacturing, the establishment of a fully automated, microfluidic, cell culture system tha...
The ability to culture individual cells provides a unique method to assess the heterogeneity of mamm...
We report on a microfluidic set-up for convenient biological experiments involving cell culture. The...
We developed an integrated microfluidic chip for long-term culture of isolated single cells. This po...
Cell culture is an extensively used technique for studying the behavior and growth of cells in respo...
Artificial animal cell culture was successfully developed by Ross Harrison in 1907. But it was not u...
In vitro microenvironments used for culturing and studying living cells have remained virtually unch...
Microfluidics is emerging as a promising platform for cell culture, enabling increased microenvironm...
In vitro study at the cellular level is an important step in evaluation of biological properties of ...
In this project, the microfludic cell culture chip and array has been designed and fabricated by co...
Cell culture has been a fundamental tool for the study of cell biology, tissue engineering, stem cel...
Lab-on-a-chip systems are promising tools in the field of cell engineering. Microfluidic systems are...
Here we present a microfluidic culture platform for enhancing single stem cell survival. Traditional...
A physiologically relevant environment is essential for successful long-term cell culturing in vitro...
Lab-on-chip systems are microfluidic devices that can be used as powerful tools for research in fiel...
In cell manufacturing, the establishment of a fully automated, microfluidic, cell culture system tha...
The ability to culture individual cells provides a unique method to assess the heterogeneity of mamm...
We report on a microfluidic set-up for convenient biological experiments involving cell culture. The...
We developed an integrated microfluidic chip for long-term culture of isolated single cells. This po...
Cell culture is an extensively used technique for studying the behavior and growth of cells in respo...
Artificial animal cell culture was successfully developed by Ross Harrison in 1907. But it was not u...
In vitro microenvironments used for culturing and studying living cells have remained virtually unch...
Microfluidics is emerging as a promising platform for cell culture, enabling increased microenvironm...