Canine Mycoplasmas

Cilj ovog diplomskog rada bio je dati pregled mikoplazama izdvojenih iz uzoraka podrijetlom od pasa. Posebno smo se osvrnuli na etiološko značenje nalaza mikoplazama u pasa s različitim kliničkim očitovanjima, a rad je objedinio dosadašnja istraživanja o mikoplazmama pasa. U 40 godina, samo 50 publikacija obuhvatilo je polje mikoplazmologije pasa što pokazuje potrebu za daljnjim istraživanjima. Do sada je poznato 15 vrsta mikoplazama koje uzrokuju bolesti u pasa. Klinička očitovanja mikoplazmoza pasa su šarolika, počevši od respiratornih bolesti, bolesti urogenitalnog trakta i steriliteta, meningoencefalomijelitisa i meningoencefalitisa, teških anemija, septikemija do artritisa. Dijagnostika, izolacija i identifikacija ovih mikroba otežana je zbog specifičnih fizioloških osobina mikoplazama, rijetko se otkrivaju, a ne reagiraju na uobičajenu terapiju antimikrobnim sredstvima. Liječe se uglavnom tetraciklinskim antibioticima, a urođeno su rezistentne na na penicilinske i cefalosporinske antibiotike. Budući da je u nekoliko navrata dokazana prisutnost mikoplazama pasa u ljudi, smatra se da su to bakterije sa zoonotskim potencijalom koji tek treba istražiti.The aim of this graduate thesis was to provide a review of isolated mycoplasmas from canine samples. We have specifically considered the aethiological significance of mycoplasmic findings in dogs with different clinical manifestations, and this work has united past researches of canine mycoplasmas. In 40 years there have been only 50 publications from canine mycoplasmology field, which means it has to be more investigated. So far, 15 types of mycoplasmas are known that cause disease in dogs. Clinical manifestations of canine mycoplasmosis are variant, ranging from respiratory tract diseases, urogenital tract diseases and sterility, meningoencephalomyelitis and meningoencephalitis, severe anemia, septicemia to arthritis. Diagnosis, isolation and identification of these microbes are hampered by the properties of mycoplasmas, they rarely reveal and do not respond to conventional antimicrobial therapy. Mycoplasmoses are mainly treated with tetracycline antibiotics, since they are resistant to penicillin and cephalosporin antibiotics. Since the presence of canine mycoplasmas in humans has been shown on several occasions, it is considered that the disease with zoonotic potential is still to be investigated