Lipase-catalyzed butyl-acetate synthesis within green solvents

Uspostavljanje novih visokoučnikovitih i održivih procesa proizvodnje industrijski važnih kemikalija predmet je mnogih znanstvenih istraživanja u području kemijske tehnologije i biotehnologije. Stoga se ionske kapljevine i eutektična otapala, nova generacija nehlapljivih i stabilnih otapala, posljednjih godina intenzivno proučavaju kao zamjena za tradicionalna i škodljiva otapala u procesima organske sinteze i biokatalize. U okviru ovog rada ispitana je mogućnost primjene kolinijevih ionskih kapljevina i eutektičnih otapala u lipazom kataliziranoj sintezi butil-acetata, estera od industrijskog značaja. Dobiveni rezultati ukazuju da su kolinijeva eutektična otapala uz dodatak vode izvrstan medij za provođenje ispitivane esterifikacije.Establishment of new highly productive and sustainable processes for the production of industrially important compounds is becoming a growing area of research in the field of chemical technology and biotechnology. Therefore, the use of ionic liquids and eutectic solvents as possible replacement for conventional molecular solvents for biocatalytic and organic reactions has recently been the subject of considerable attention. Within this work cholinium-based ionic liquids and eutectic solvents were prepared and tested as solvents for lipase-catalyzed butyl-acetate synthesis. Obtained results imply that cholinium-based eutectic solvents with addition of certain amount of water are excelent medium for tested esterification