The oscillations of calcium, phopshates, potassium and parathyroid hormone in hemodialysis treated patients with end-stage chronic kidney disease

Uvod: Oko 500 milijuna ljudi ima neki stupanj KBB. U KBB zahvaćeni su svi organski sustavi. Postoje precizne smjernice kada i kako ih liječiti. Cilj istraživanja: Provjeriti imaju li bolesnici s KBB liječeni hemodijalizom oscilacije kalcija, fosfata, PTH i kalija i jesu li te oscilacije značajne. Nadalje, cilj istraživanja bila je provjera jesu li te oscilacije češće u žena nego muškaraca, češće u onih koji žive na selu od onih koji žive u gradu, provjera utječe li trajanje liječenja hemodijalizom na razine navedenih parametara i postoje li razlike između onih koji vezače fosfata i/ili vitamin D uzimaju redovito ili neredovito. Ispitanici i metode: U istraživanje je bilo uključeno 100 bolesnika sa završnim stupnjem KBB liječenih HD u razdoblju od rujna 2015. godine do listopada 2016. godine. Provedena je anketa u svrhu provjere redovitog uzimanja vezača fosfata i vitamina D. Rezultati: Od 100 ispitanika, bilo 55 je muškaraca i 45 žena. Medijan dobi ispitanika bio je 68 godina, a dobi u vrijeme početka liječenja HD 63 godine. Medijan trajanja liječenja HD bio je 4 godine. Nije bilo statistički značajnih razlika između žena i muškaraca u dobi i u trajanju liječenja HD. Zaključak: Bolesnici s KBB liječeni hemodijalizom imaju oscilacije kalcija, fosfata, PTH i kalija. Žene su imale rjeđe oscilacije navedenih parametara od muškaraca. Postoje razlike promatranih parametara između bolesnika koji žive na selu i onih koji žive u gradu.Introduction: About 500 million people are suffering from one of the stages of chronic kidney disease. CKD affects all organ systems. There are precise guidelines on when and how to treat them. Goal of the research: To check whether CKD patients who received haemodialysis treatments have calcium, phosphates, PTH, and potassium oscillations, and whether they are significant. Check if the oscillations are more frequent in women than in men or if the oscillations are more frequent in those patients who live in the country than in those living in the city. Check whether the duration of haemodialysis affects the levels of the stated parameters and if there are differences between those who take phosphate binders and/or vitamin D irregularly and regularly. Research participants and methods: Research participants were 100 patients with final stage CKD treated with HD in the period from September of 2015 to October of 2016. A survey was implemented for the purpose of creating an overview of regularity concerning phosphorous binder and vitamin D therapies. Results: Out of 100 research participants, there were 55 men and 45 women. The median age of the test subjects was 68 with the appropriate, and the median age at first HD was 63. The median HD duration was 4 years. There were no statistically significant differences in age and HD duration, or in the place of residence and according to the sex of the research participants. Conclusion: Patients with CKD who received haemodialysis treatments have calcium, phosphates, PTH, and potassium oscillations. Women have less frequent oscillations regarding the stated parameters than men. There are differences in parameters between the patients who live in the country and those who live in the city. There are differences in the stated parameters between the patients who live in the country and those who live in the city