Add to ORKGalpha-Aminonitriles with a mono- or unsubstituted amino group as well as alpha(alkylideneaminomitriles can be employed as easily accessible alpha-aminocarbanion equivalents. Their alpha-deprotonation yields stabilized carbanions, which undergo smooth 1,4-addition to alpha,beta-unsaturated carbonyl compounds. The resulting delta-keto-alpha-aminonitriles can be reductively cyclized to form polysubstituted pyrrolidines
Multifunctionalized pyrrole derivatives were synthesized using a highly efficient method based on th...
The cyanobis(dibenzylamino)borane-mediated transformation of chiral aldehydes into the corresponding...
The reaction of nitroalkanes with 2-chloro-3-phenylsulfonylpropanenitrile, in the presence of three ...
The vinylogous addition of deprotonated N-alkyl-alpha-aminonitriles to alpha,beta-unsaturated carbon...
alpha-(Alkylideneamino)nitriles can be deprotonated under mild conditions. Their conjugated anions r...
The reaction of alpha,beta-unsaturated carbonyl compounds with aminoacetonitrile hydrochloride furni...
alpha-Aminonitriles and alpha-(alkylideneamino)nitriles can serve as readily available alpha-aminoca...
Viele substituierte Pyrrolidine zeigen eine hohe Affinität zu biologischen Makromolekülen wie zu G-P...
Fully substituted 4-aminopyrrolones are easily accessed via simple routes starting from imines, keto...
This review highlights various aspects of the chemistry of the anions of alpha-aminonitriles. Their ...
A series of 1,2,4-trisubstituted pyrroles have been synthesized in 83-96% yields on treatment of chi...
The objective of this investigation was to develop a new synthetic method for the asymmetric synthes...
An unprecedented nucleophilic addition/cyclization/aromatization cascade of basic chemicals, i.e., a...
Allylsilanes preapared from alpha-aminoacids react with acyl chlorides in the presence of TiCl4 to g...
Reaction of deprotonated alpha-(alkylidenamino)nitriles with gramine in the presence of tributylphos...
Multifunctionalized pyrrole derivatives were synthesized using a highly efficient method based on th...
The cyanobis(dibenzylamino)borane-mediated transformation of chiral aldehydes into the corresponding...
The reaction of nitroalkanes with 2-chloro-3-phenylsulfonylpropanenitrile, in the presence of three ...
The vinylogous addition of deprotonated N-alkyl-alpha-aminonitriles to alpha,beta-unsaturated carbon...
alpha-(Alkylideneamino)nitriles can be deprotonated under mild conditions. Their conjugated anions r...
The reaction of alpha,beta-unsaturated carbonyl compounds with aminoacetonitrile hydrochloride furni...
alpha-Aminonitriles and alpha-(alkylideneamino)nitriles can serve as readily available alpha-aminoca...
Viele substituierte Pyrrolidine zeigen eine hohe Affinität zu biologischen Makromolekülen wie zu G-P...
Fully substituted 4-aminopyrrolones are easily accessed via simple routes starting from imines, keto...
This review highlights various aspects of the chemistry of the anions of alpha-aminonitriles. Their ...
A series of 1,2,4-trisubstituted pyrroles have been synthesized in 83-96% yields on treatment of chi...
The objective of this investigation was to develop a new synthetic method for the asymmetric synthes...
An unprecedented nucleophilic addition/cyclization/aromatization cascade of basic chemicals, i.e., a...
Allylsilanes preapared from alpha-aminoacids react with acyl chlorides in the presence of TiCl4 to g...
Reaction of deprotonated alpha-(alkylidenamino)nitriles with gramine in the presence of tributylphos...
Multifunctionalized pyrrole derivatives were synthesized using a highly efficient method based on th...
The cyanobis(dibenzylamino)borane-mediated transformation of chiral aldehydes into the corresponding...
The reaction of nitroalkanes with 2-chloro-3-phenylsulfonylpropanenitrile, in the presence of three ...