Reaction of deprotonated alpha-(alkylidenamino)nitriles with gramine in the presence of tributylphosphine furnishes alpha-substituted imines of tryptophane nitrile. Their subsequent intramolecular cyclization followed by dehydrocyanation and oxidation affords 1,3-disubstituted beta-carbolines
AbstractEthyl 2-aryl-3-dimethylamino-acrylates 2a,b were prepared via the reaction of ethyl arylacet...
A new solution-phase methodology microwave-assisted for improving the Pictet-Spengler reaction in th...
A new solution-phase methodology microwave-assisted for improving the Pictet-Spengler reaction in th...
The synthesis of 3-carbomethoxy-1,4-dimethyl-acarboline (50a), 3-carbomethoxy-l-ethyl-4-methyl-~carb...
The alpha-alkylation of deprotonated N-aryl-alpha-aminonitriles with alpha-bromoesters furnishes int...
The reaction of alpha,beta-unsaturated carbonyl compounds with aminoacetonitrile hydrochloride furni...
alpha-Aminonitriles with a mono- or unsubstituted amino group as well as alpha(alkylideneaminomitril...
One-pot efficient and simple synthesis of γ-carboline derivatives by the Graebe-Ullmann method was c...
The vinylogous addition of deprotonated N-alkyl-alpha-aminonitriles to alpha,beta-unsaturated carbon...
The synthesis of 3-substituted 1-methylpyrrolo[1,2-a]pyrazines and 3-substituted isoquinolines was a...
2-Acyl-1-benzenesulfonyl-3-iodo-1H-indoles and 1-benzenesulfonyl-3-iodo-1H-indole-2-carbaldehyde giv...
The reaction of aldehydes, amines and TMSCN in the presence of 2-iodoxybenzoic acid (IBX) and tetrab...
A strategy for the preparation of 3-vinyl-2-alkylidene-3-cyclohexen-1-ones has been developed using ...
International audienceThe synthesis of 2-, 3-, and 4-substituted alpha-carbolines is described start...
The synthesis of [a]-annelated pyrazolopyrroloindoles via intramolecular 1,3-dipolar cycloaddition o...
AbstractEthyl 2-aryl-3-dimethylamino-acrylates 2a,b were prepared via the reaction of ethyl arylacet...
A new solution-phase methodology microwave-assisted for improving the Pictet-Spengler reaction in th...
A new solution-phase methodology microwave-assisted for improving the Pictet-Spengler reaction in th...
The synthesis of 3-carbomethoxy-1,4-dimethyl-acarboline (50a), 3-carbomethoxy-l-ethyl-4-methyl-~carb...
The alpha-alkylation of deprotonated N-aryl-alpha-aminonitriles with alpha-bromoesters furnishes int...
The reaction of alpha,beta-unsaturated carbonyl compounds with aminoacetonitrile hydrochloride furni...
alpha-Aminonitriles with a mono- or unsubstituted amino group as well as alpha(alkylideneaminomitril...
One-pot efficient and simple synthesis of γ-carboline derivatives by the Graebe-Ullmann method was c...
The vinylogous addition of deprotonated N-alkyl-alpha-aminonitriles to alpha,beta-unsaturated carbon...
The synthesis of 3-substituted 1-methylpyrrolo[1,2-a]pyrazines and 3-substituted isoquinolines was a...
2-Acyl-1-benzenesulfonyl-3-iodo-1H-indoles and 1-benzenesulfonyl-3-iodo-1H-indole-2-carbaldehyde giv...
The reaction of aldehydes, amines and TMSCN in the presence of 2-iodoxybenzoic acid (IBX) and tetrab...
A strategy for the preparation of 3-vinyl-2-alkylidene-3-cyclohexen-1-ones has been developed using ...
International audienceThe synthesis of 2-, 3-, and 4-substituted alpha-carbolines is described start...
The synthesis of [a]-annelated pyrazolopyrroloindoles via intramolecular 1,3-dipolar cycloaddition o...
AbstractEthyl 2-aryl-3-dimethylamino-acrylates 2a,b were prepared via the reaction of ethyl arylacet...
A new solution-phase methodology microwave-assisted for improving the Pictet-Spengler reaction in th...
A new solution-phase methodology microwave-assisted for improving the Pictet-Spengler reaction in th...