Colon cancer is still one of the leading causes of cancer death worldwide. Although the host immune system has been shown to react against tumor cells, mainly through tumor infiltrating lymphocytes and NK cells, tumor cells may utilize different ways to escape anti-tumor immune response. Tumor infiltration of CD8 and CD4 (T-bet ) effector T cells has been attributed to a beneficial outcome, and the enhancement of T cell activation through T cell receptor stimulation and co-stimulatory signals provides promising strategies for immunotherapy of colon cancer. Growing evidence supports a role for the Fas/FasL system in tumor immunology, although the mechanisms and consequences of FasL activation in colon cancer are not completely understood. ...
Background: T lymphocytes exert important homeostatic functions in the healthy intestinal mucosa, wh...
International audienceBACKGROUND: The antitumoral immune response is one determinant of colorectal c...
Worldwide, more than one million people are diagnosed with colorectal cancer (CRC) every year. Analy...
Colorectal cancer usually gives rise to a specific anti-tumor immune response, but for unknown reaso...
BACKGROUND: Colorectal cancer usually gives rise to a specific anti-tumor immune response, but for u...
AIM: To determine the role of Fas/Fas ligand (FasL) in the immune escape of colon cancer cells. METH...
Colorectal cancer is one of the most common malignant diseases, with an annual incidence of over one...
Recent results have shown a correlation between survival and frequency of tumour infiltrating T lymp...
: In recent years, research has focused on colorectal cancer to implement modern treatment approache...
Colon cancer comprises a small population of cancer initiating stem cells (CIC) that is responsible ...
Although most cancer types have been viewed as immunologically silent until recently, it has become ...
Tumor-infiltrating lymphocytes (TIL) are crucial for anti-tumor immunity. However, regulatory T cell...
γδ T cells are capable of recognizing tumor cells and exert potent cellular cytotoxicity against a l...
<div><p>Colon cancer comprises a small population of cancer initiating stem cells (CIC) that is resp...
Immunotherapies have achieved clinical benefit in many types of cancer but remain limited to a subse...
Background: T lymphocytes exert important homeostatic functions in the healthy intestinal mucosa, wh...
International audienceBACKGROUND: The antitumoral immune response is one determinant of colorectal c...
Worldwide, more than one million people are diagnosed with colorectal cancer (CRC) every year. Analy...
Colorectal cancer usually gives rise to a specific anti-tumor immune response, but for unknown reaso...
BACKGROUND: Colorectal cancer usually gives rise to a specific anti-tumor immune response, but for u...
AIM: To determine the role of Fas/Fas ligand (FasL) in the immune escape of colon cancer cells. METH...
Colorectal cancer is one of the most common malignant diseases, with an annual incidence of over one...
Recent results have shown a correlation between survival and frequency of tumour infiltrating T lymp...
: In recent years, research has focused on colorectal cancer to implement modern treatment approache...
Colon cancer comprises a small population of cancer initiating stem cells (CIC) that is responsible ...
Although most cancer types have been viewed as immunologically silent until recently, it has become ...
Tumor-infiltrating lymphocytes (TIL) are crucial for anti-tumor immunity. However, regulatory T cell...
γδ T cells are capable of recognizing tumor cells and exert potent cellular cytotoxicity against a l...
<div><p>Colon cancer comprises a small population of cancer initiating stem cells (CIC) that is resp...
Immunotherapies have achieved clinical benefit in many types of cancer but remain limited to a subse...
Background: T lymphocytes exert important homeostatic functions in the healthy intestinal mucosa, wh...
International audienceBACKGROUND: The antitumoral immune response is one determinant of colorectal c...
Worldwide, more than one million people are diagnosed with colorectal cancer (CRC) every year. Analy...