Medical applications of plant secondary metabolites

Kemija, farmakologija i medicina obraća sve veću pozornost na sekundarne metabolite biljaka kao potencijalne lijekove ili polazne spojeve za sintezu lijekova. Opisana su terapeutska svojstva spojeva i standardiziranih ekstrakata biljnog podrijetla koji su posljednjih 10 godina privukli veliku pozornost u smislu njihove medicinske primjene. Najveći dio rada je usmjeren na spojeve s antitumorskim i kemoprevencijskim djelovanjem. Nadalje navedene su biljke i ekstrakti s antivirusnim i antimalarijskim djelovanjem te s protuupalnim, antidepresijskim, anti-ishemijskim i imunostimulativnim djelovanjem.Chemistry, farmacology and medicine pay more and more attention to plants secondary metabolites as potential drugs or starting compounds for drug synthesis. Therapeutic properties of various compounds and standardized extracts of plant origin have been described, whose medical application has drawn attention for the last 10 years. The biggest part of this thesis is focuses on compounds with anticancer and chemopreventive activity. In addition, plants and extracts with antiviral and antimalarial activity as well as antiinflammatory, antidepressant, anti-ischaemic and immunostimulatory activity, have been descuses