Lithiated (alfa-chloroalkyl)heterocycles, generated by deprotonation with LDA at -78 °C in THF, add to various enantiopure imines affording ‘one pot’ chiral heterosubstituted aziridines in a diastereoselective manner. Lithiated heterosubstituted aziridines, obtained by deprotonation of the corresponding aziridines with n-BuLi at -78 °C in THF, were trapped by electrophiles (D2O or CH3I) with high stereoselectivity
Small heterocyclic rings constitute systems of central importance in theoretical, synthetic organic,...
Deprotonation of terminal epoxides and aziridines with organolithium/ diamine combinations or lithiu...
Upon treatment with the K- and Li-enolates of a methylene active compound, such as dimethyl malonate...
Lithiated (alpha-chloroalkyl)heterocycles, generated by deprotonation with LDA at -78 °C in THF, add...
1,2,3-triHeterocycle-substituted aziridines were prepared by coupling of (alfa-chloroalkyl) oxazolin...
A highly stereo- and regioselective functionalisation of chiral nonracemic aziridines is reported....
alpha,alpha-Disubstituted aziridines can be produced in good yields by selective lithiation of N-ter...
alpha,alpha-Disubstituted aziridines can be produced in good yields by selective lithiation of N-ter...
The lithiation reaction of o-tolylaziridine 1 has been investigated by using the aziridine ring cap...
A direct synthetic procedure to obtain chiral aziridines is reported, involving a diastereoselective...
Aziridines continue to offer synthetic interest, whilst providing important intermediates in the pre...
The aza-Darzens ('ADZ') reactions of N-diphenylphosphinyl ('N-Dpp') imines with chiral enolates deri...
[[abstract]]Aziridine is an important building block found in many nature products. The preparation ...
The aza-Darzens (‘ADZ’) reactions of N-diphenylphosphinyl (‘N-Dpp’) imines with chiral enolates deri...
Some recent advances in the field of stereoselective synthesis of aziridines focusing on new methodo...
Small heterocyclic rings constitute systems of central importance in theoretical, synthetic organic,...
Deprotonation of terminal epoxides and aziridines with organolithium/ diamine combinations or lithiu...
Upon treatment with the K- and Li-enolates of a methylene active compound, such as dimethyl malonate...
Lithiated (alpha-chloroalkyl)heterocycles, generated by deprotonation with LDA at -78 °C in THF, add...
1,2,3-triHeterocycle-substituted aziridines were prepared by coupling of (alfa-chloroalkyl) oxazolin...
A highly stereo- and regioselective functionalisation of chiral nonracemic aziridines is reported....
alpha,alpha-Disubstituted aziridines can be produced in good yields by selective lithiation of N-ter...
alpha,alpha-Disubstituted aziridines can be produced in good yields by selective lithiation of N-ter...
The lithiation reaction of o-tolylaziridine 1 has been investigated by using the aziridine ring cap...
A direct synthetic procedure to obtain chiral aziridines is reported, involving a diastereoselective...
Aziridines continue to offer synthetic interest, whilst providing important intermediates in the pre...
The aza-Darzens ('ADZ') reactions of N-diphenylphosphinyl ('N-Dpp') imines with chiral enolates deri...
[[abstract]]Aziridine is an important building block found in many nature products. The preparation ...
The aza-Darzens (‘ADZ’) reactions of N-diphenylphosphinyl (‘N-Dpp’) imines with chiral enolates deri...
Some recent advances in the field of stereoselective synthesis of aziridines focusing on new methodo...
Small heterocyclic rings constitute systems of central importance in theoretical, synthetic organic,...
Deprotonation of terminal epoxides and aziridines with organolithium/ diamine combinations or lithiu...
Upon treatment with the K- and Li-enolates of a methylene active compound, such as dimethyl malonate...