BONE MARROW STROMAL CELLS RESPONSE TO FLUORIDE-MODIFIED IMPLANT SURFACES

Background: The possibility to enhance the biological performance of dental implants by modulating their topographycal and chemical surface features represents a growing aspect of dental research. Fluoride ion incorporation into titanium surfaces has been suggested to positively affect bone cell and tissue response. Being the precursors of the entire osteoblastic lineage, bone marrow stromal cells play a central role in osteogenesis and bone reparative mechanisms, representing an ideal tool to investigate the interaction between bone cells and implant surface