The charged fermion masses of the three generations exhibit the two strong hierarchies m3≫m2≫m1 . We assume that also neutrino masses satisfy mν3>mν2>mν1 and derive the consequences of the hierarchical spectra on the fermionic mixing patterns. The quark and lepton mixing matrices are built in a general framework with their matrix elements expressed in terms of the four fermion mass ratios, mu/mc , mc/mt , md/ms and ms/mb , and me/mμ , mμ/mτ , mν1/mν2 and mν2/mν3 , for the quark and lepton sector, respectively. In this framework, we show that the resulting mixing matrices are consistent with data for both quarks and leptons, despite the large leptonic mixing angles. The minimal as...