Sorption of nitrofurantoin onto natural sediments

Nitrofurantoin je nitrofuranski antibakterijski lijek koji se najčešće koristi kao veterinarski farmaceutik. Ovaj spoj kao i ostali farmaceutici uvelike može utjecati na okoliš, na tlo i organizme u njemu te zagaditi vodene ekosustave izlučivanjem fekalija i urina uz raspršivanje i otjecanjem s polja. S obzirom da je u upotrebi svega nekoliko desetljeća, o njegovoj sudbini i ponašanju u okolišu vrlo malo se zna. Stoga su u ovom radu određeni parametri sorpcije nitrofurantoina na prirodne sedimente s područja Republike Hrvatske pomoću Freundlichove i Dubinin-Radushkevichove izoterme. Dobiveni koeficijenti sorpcije (Kd) za sedam uzoraka sedimenata kreću se u rasponu od 3,967-5,121 mL/g. Također ispitani su utjecaji fizikalno-kemijskih karakteristika sedimenata kao i spomenutog farmaceutika te utjecaj ionske jakosti na stupanj sorpcije, pri čemu rezultati pokazuju da se povećanjem ionske jakosti smanjuje koeficijent sorpcije.Nitrofurantoin is nitrofuran antibacterial drug that is most used as a veterinary pharmaceutic compound. This compound, as well as other pharmaceuticals can greatly affect the enviroment, the soil and organisms in it and pollute aquatic ecosystems by excretion of feces and urine with dispersion and runoff from the field. Since the use of only a few decades, knowledge of their fate and behavior in the environment is still limited. Therefore, in this study determined sorption parameters of nitrofurantoin in natural sediments from Croatia using Freundlich and Dubinin-Radushkevich isotherms. Obtained sorption coefficients (Kd) for seven sediment samples are ranged from 3,967-5,121 mL/g. Also tested the effects of physical-chemical properties of sediments as well as the mentioned pharmaceutical and ionic strength effects on the degree of sorption, where the results show that an increase in ionic strength reduces the values of sorption coefficient