Control of helical chirality in supramolecular chromophore-DNA architectures

Four different D- and L-configured chromophore–20-deoxyuridine conjugates were applied to elucidate the helical chirality of their non-covalent assemblies along the D- and L-configured DNA templates by optical spectroscopy. There is no configuration-selective recognition between these nucleosides and the DNA templates. The helicity of the DNA assemblies is either controlled by the configuration of the DNA template or by the nucleoside configuration