© 2016 Elsevier Ltd. All rights reserved.Multivalent interactions play an essential role in molecular recognition in living systems. These effects were employed to target tumor cells using albumin clusters bearing ∼10 molecules of asparagine-linked glycans (N-glycans). Noninvasive near-infrared fluorescence imaging clearly revealed A431 tumors implanted in BALB/cA-nu/nu mice after 1 h in an N-glycan structure-dependent manner, thereby demonstrating the efficient use of glycan multivalency effects for tumor targeting in vivo
Glycosylation is an enzymatic process through which glycans attach to proteins, lipids and other org...
© 2015 Springer Science+Business Media New York. While many examples have been reported that glycocl...
Aim: Fragment crystallizable (Fc) glycans modulate Fc conformations and functions, and glycan may al...
© 2016 Elsevier Ltd. All rights reserved.Multivalent interactions play an essential role in molecula...
A series of N-glycans, each sequentially trimmed from biantennary sialoglycans, were homo- or hetero...
A series of N-glycans, each sequentially trimmed from biantennary sialoglycans, were homo-or heterog...
© 2020, The Author(s). In the field of molecular imaging, selectivity for target cells is a key dete...
© 2020 Wiley-VCH GmbH Natural glycoconjugates that form glycocalyx play important roles in various b...
Stimulation of the body's immune system toward tumor cells is now well recognized as a promising str...
Although it has been well known that dynamic changes in glycosylation are associated with tumor prog...
Cell surfaces feature abundant glycosylation. Glycans adorn roughly 90% of cell surface proteins and...
Cancer cells generally exhibit higher metabolic demands relative to that of normal tissue cells. Thi...
The preparation of heterogeneous glycoclusters on human serum albumin, containing two structurally n...
Aberrant changes in specific glycans have been shown to be associated with immunosurveillance, tumor...
Glycans are essential regulators of protein function and are now in the focus of research in many ph...
Glycosylation is an enzymatic process through which glycans attach to proteins, lipids and other org...
© 2015 Springer Science+Business Media New York. While many examples have been reported that glycocl...
Aim: Fragment crystallizable (Fc) glycans modulate Fc conformations and functions, and glycan may al...
© 2016 Elsevier Ltd. All rights reserved.Multivalent interactions play an essential role in molecula...
A series of N-glycans, each sequentially trimmed from biantennary sialoglycans, were homo- or hetero...
A series of N-glycans, each sequentially trimmed from biantennary sialoglycans, were homo-or heterog...
© 2020, The Author(s). In the field of molecular imaging, selectivity for target cells is a key dete...
© 2020 Wiley-VCH GmbH Natural glycoconjugates that form glycocalyx play important roles in various b...
Stimulation of the body's immune system toward tumor cells is now well recognized as a promising str...
Although it has been well known that dynamic changes in glycosylation are associated with tumor prog...
Cell surfaces feature abundant glycosylation. Glycans adorn roughly 90% of cell surface proteins and...
Cancer cells generally exhibit higher metabolic demands relative to that of normal tissue cells. Thi...
The preparation of heterogeneous glycoclusters on human serum albumin, containing two structurally n...
Aberrant changes in specific glycans have been shown to be associated with immunosurveillance, tumor...
Glycans are essential regulators of protein function and are now in the focus of research in many ph...
Glycosylation is an enzymatic process through which glycans attach to proteins, lipids and other org...
© 2015 Springer Science+Business Media New York. While many examples have been reported that glycocl...
Aim: Fragment crystallizable (Fc) glycans modulate Fc conformations and functions, and glycan may al...