Complexes of a novel N-(diisopropxythiophosphoryl)thiourea derivative of 1,4,8,11-tetraazacyclotetradecane with Na+, K+ and Cu (PPh3)2 + cations

The reaction between 1,4,8,11-tetraazacyclotetradecane (cyclam) and O,O′-diisopropyl-isothiocyanatothiophosphoric acid (iPrO)2P(S)NCS gives the tetra-functional thiourea H4L with four C(S)NHP(S)(OPri)2 groups attached to the intracyclic nitrogen atoms. The tetra-substituted product has been obtained in the solid state, while partial dissociation with elimination of isothiocyanate (iPrO)2P(S)NCS takes place in CCl4 and CDCl3 solutions. Deprotonation of the exocyclic groups prevents the dissociation, and alkali metal salts of M4L formula (M = Na+, K+) were obtained by treatment with MOH. The potassium salt K4L was used to synthesize the Cu(I) complex [{Cu(PPh3)2}4L] by reaction with Cu(PPh3)3I. © 2006 Elsevier Ltd. All rights reserved