Effect of the RNase from bacillus intermedium on the trophic organization of the mitotic cycle of candida utilis

The effect of the RNase from Bacillus intermedius on the growth and trophic cycle of Candida utilis was studied. The RNase at concentrations of 0.001-0.01 μg/ml stimulated yeast growth by 30-40% as compared to the control, reduced the mitotic cycle of the yeast by shortening its Gl phase, and decreased the number of exotrophic cells in the Gl phase to a minimum. It was suggested that RNase is involved in the regulation of the transition of cells from the exo- to endotrophic state