Nicotine has been reported to increase the intracellular Ca2+ concentration ([Ca2+]i) in sublingual acini due to neurotransmitter release from nerve terminals associated with the cell preparation (1). However, it is unclear whether or not the same reaction exists in parotid cells. Therefore, we investigated effect of nicotine on Ca2+ mobilization in digested parotid acini from rats. After removing the parotid gland from Wistar rats, the tissues were minced and digested with collagenase. Then, the intracellular Ca2+ indicator fura-2 was added to the preparation, and the change in [Ca2+]i was monitored using fluorescent microscope. In many but not all parotid acini, K+ stimulation induced transient increases in [Ca2+]i. The K+-induced Ca2+ re...
The crucial effects of chronic nicotine exposure are intracellular and include a cell-specific influ...
In this study, we demonstrate the existence on trigeminal caudal nucleus (TCN) glutamatergic termina...
Neuromodulatory systems of the brain have been suggested to profoundly impact on neurotransmission a...
AbstractöWhile nicotine is known to act at neuronal nicotinic acetylcholine receptors (nAChRs) to fa...
Presynaptic nicotinic acetylcholine receptors (nAChRs) have long been implicated in the modulation o...
Background Nicotine is a risk factor for pancreatitis resulting in loss of pancreatic enzyme secreti...
The pathway from the medial habenular nucleus to the interpeduncular nucleus, in which nicotinic ace...
Two distinct native alpha-bungarotoxin (alpha-Bgt)-insensitive nicotinic acetylcholine receptors (nA...
<div><p><b>A</b>: Schematic of experimental protocols. a1: Spinning disk confocal images from live W...
Nicotine acetylcholine (ACh) receptors (nAChRs) are ligand‐gated ion channels that are widely expres...
In cultured mouse C2C12 myotubes, digital Ca2+ imaging fluorescence microscopy using the acetoxymeth...
We have previously shown that activation of nicotinic acetylcholine receptors (nAChRs) enhanced long...
Background: Chronic obstructive pulmonary disease (COPD) is characterized by airway remodeling with ...
The nicotine-induced modulation of the synaptic activity was studied in cultured spinal cord neurons...
Producción CientíficaCurrent concepts on the location and functional significance of nicotinic recep...
The crucial effects of chronic nicotine exposure are intracellular and include a cell-specific influ...
In this study, we demonstrate the existence on trigeminal caudal nucleus (TCN) glutamatergic termina...
Neuromodulatory systems of the brain have been suggested to profoundly impact on neurotransmission a...
AbstractöWhile nicotine is known to act at neuronal nicotinic acetylcholine receptors (nAChRs) to fa...
Presynaptic nicotinic acetylcholine receptors (nAChRs) have long been implicated in the modulation o...
Background Nicotine is a risk factor for pancreatitis resulting in loss of pancreatic enzyme secreti...
The pathway from the medial habenular nucleus to the interpeduncular nucleus, in which nicotinic ace...
Two distinct native alpha-bungarotoxin (alpha-Bgt)-insensitive nicotinic acetylcholine receptors (nA...
<div><p><b>A</b>: Schematic of experimental protocols. a1: Spinning disk confocal images from live W...
Nicotine acetylcholine (ACh) receptors (nAChRs) are ligand‐gated ion channels that are widely expres...
In cultured mouse C2C12 myotubes, digital Ca2+ imaging fluorescence microscopy using the acetoxymeth...
We have previously shown that activation of nicotinic acetylcholine receptors (nAChRs) enhanced long...
Background: Chronic obstructive pulmonary disease (COPD) is characterized by airway remodeling with ...
The nicotine-induced modulation of the synaptic activity was studied in cultured spinal cord neurons...
Producción CientíficaCurrent concepts on the location and functional significance of nicotinic recep...
The crucial effects of chronic nicotine exposure are intracellular and include a cell-specific influ...
In this study, we demonstrate the existence on trigeminal caudal nucleus (TCN) glutamatergic termina...
Neuromodulatory systems of the brain have been suggested to profoundly impact on neurotransmission a...