Add to ORKGThe aim of this study was to elucidate what sort of gastric adenoma transforms into malignancy and where cancer develops in adenomatous tubule. The object was 111 gastric adenomas and 10 carcinoma arising in adenoma. p53 and Ki-67 immunostaing was performed for objective detection of small foci of microscopic carcinoma. Malignant transformation was found only in adenoma of high-grade cytological atypia and of 19mm or more in size. The rate was 8.3% (10/121) in total, 0% (0/71) in tumors less than 10mm, 8.7% (2/23) in 10≦x<20mm tumors, and 29.2% (8/27) in 20≦x tumors. Microscopic cancer was found in the proliferative zone (superficial layer) of adenomatous tubules by p53 immunostaing. The cancer tissue was of low-grade in cytological atypia,...
Gastric Cancer Is The Third Most Common Cancer In India And The Second Most Common Type Of Cancer W...
Immunohistochemistry staining of p53 is a cheap and simple method to detect aberrant function of p53...
Context. Immunohistochemical stains for p53 are used as a diagnostic marker associated with malignan...
Morphological characteristics of gastric adenoma were investigated using 107 lesions (79 cases) of a...
The aim of this study was to investigate the immunohistochemical expression of p53 and Ki67 in color...
We screened for p53 alterations in 71 early gastric cancers of differing histological types and grow...
p53 protein immunoexpression was evaluated in 17 invasive carcinomas arising in pleomoqhic adenoma a...
Molecular abnormalities of the p53 gene in chromosome 17p may be among the most commonly observed in...
histochemistry A b s t r a c t Of 987 cases of gastric adenocarcinoma seen at Nagoya University Scho...
P53 overexpression, detected by immunohistochemical analysis, has been reported in about 50% of gast...
Abstract Background Although the gastric well-differentiated adenocarcinoma in the distal stomach ha...
It has been postulated that chronic atrophic gastritis, intestinal metaplasia, and dysplasia are pre...
This study was carried out for evaluating the interplay of p53, p21 and Ki-67 proteins along the col...
Subject headings Ki-67 antigen; neoplasms metastasis; immunoc hemistry; DNA ploidy; stom-ach neo...
The aim of the study was to verify the presence of mutated tumor suppresser gene p53 in intestinal m...
Gastric Cancer Is The Third Most Common Cancer In India And The Second Most Common Type Of Cancer W...
Immunohistochemistry staining of p53 is a cheap and simple method to detect aberrant function of p53...
Context. Immunohistochemical stains for p53 are used as a diagnostic marker associated with malignan...
Morphological characteristics of gastric adenoma were investigated using 107 lesions (79 cases) of a...
The aim of this study was to investigate the immunohistochemical expression of p53 and Ki67 in color...
We screened for p53 alterations in 71 early gastric cancers of differing histological types and grow...
p53 protein immunoexpression was evaluated in 17 invasive carcinomas arising in pleomoqhic adenoma a...
Molecular abnormalities of the p53 gene in chromosome 17p may be among the most commonly observed in...
histochemistry A b s t r a c t Of 987 cases of gastric adenocarcinoma seen at Nagoya University Scho...
P53 overexpression, detected by immunohistochemical analysis, has been reported in about 50% of gast...
Abstract Background Although the gastric well-differentiated adenocarcinoma in the distal stomach ha...
It has been postulated that chronic atrophic gastritis, intestinal metaplasia, and dysplasia are pre...
This study was carried out for evaluating the interplay of p53, p21 and Ki-67 proteins along the col...
Subject headings Ki-67 antigen; neoplasms metastasis; immunoc hemistry; DNA ploidy; stom-ach neo...
The aim of the study was to verify the presence of mutated tumor suppresser gene p53 in intestinal m...
Gastric Cancer Is The Third Most Common Cancer In India And The Second Most Common Type Of Cancer W...
Immunohistochemistry staining of p53 is a cheap and simple method to detect aberrant function of p53...
Context. Immunohistochemical stains for p53 are used as a diagnostic marker associated with malignan...