A Study of Malignant Lymphomas(20th Meeting of the Niigata Society of Hematologic Neoplasm The Ten-year Anniversary Symposium : Progress in Hematologic Neoplasm over the Ten Years)

We review and classify 234 cases of non-Hodgkin's lymphomas which were diagnosed in our hospital during past eleven years, according to LSG classification. 74 cases of nodal lymphomas and 160 cases of extra-nodal lymphomas are divided. Concerning extranodal lymphomas, individual organ shows some characteristics of LSG classification. We make an immunohistochemical study of gastric lymphoproliferative diseases, using immunogold-silver staining method. The result indicates that we must be cautious in diagnosis of gastric non-Hodgkin's lymphomas, particularly small cell type. We also make an immunohistochemical study of Hodgkin's diseases, using several monoclonal antibodies including Ki-1, LeuM1, MT1 and SL-26. The result reveals that Ki-1 and LeuM1 are reliable markers of Hodgkin's cells. Examinations of both Ki-1 and LeuM1 are necessary to diagnosis of Hodgkin's disease