There are many macrophages in the atherosclerotic lesion. Mononuclear cells begin to migrate into the subendothelial space at the early stage of atherogenesis. They take up denatured low density lipoprotein through scavenger receptors and become lipid-laden foam cells. Various cytokines and growth factors produced by macrophages can modulate the growth and many other functions of vascular cells in vitro. Those cytokines might be secreted in the arterial wall and play an important role in atherogenesis
Cardiovascular disease is the biggest killer globally and the principal contributing factor to the p...
Atherosclerosis is a chronic inflammatory disease occurring within the artery wall and is an underly...
Multi-ligand, cell surface receptors for modified lipoproteins are called scavenger receptors. They ...
A wide variety of cell populations, including both immune and endothelial cells, participate in the ...
Atherosclerosis is the major cause of death in western countries and is also becoming a serious heal...
In atherosclerosis, the accumulation of apolipoprotein B-lipoproteins in the matrix beneath the endo...
Subendothelial macrophages are a major cellularcomponent of atherosclerotic lesions. In response tos...
Atherosclerosis is still one of the main causes of death around the globe. This condition leads to v...
Cardiovascular disease, a leading cause of mortality in developed countries, is mainly caused by ath...
Inflammatory monocytes and macrophages are innate im-mune cells that promote the growth and complica...
<p>Monocytes differentiate into macrophages which endocytose ox-LDL and become foam cells. SMCs are ...
In the development of atherosclerotic lesions, three basic processes occur: 1) invasion of the arter...
<p>LDL and HDL are oxidized by free radicals, and become ox-LDL and ox-HDL respectively. Ox-LDL recr...
Atherosclerosis can be regarded as chronic inflammatory disease driven by lipid accumulation in the ...
Human monocytes are known to be multifunctional cells that combine a variety of functions, including...
Cardiovascular disease is the biggest killer globally and the principal contributing factor to the p...
Atherosclerosis is a chronic inflammatory disease occurring within the artery wall and is an underly...
Multi-ligand, cell surface receptors for modified lipoproteins are called scavenger receptors. They ...
A wide variety of cell populations, including both immune and endothelial cells, participate in the ...
Atherosclerosis is the major cause of death in western countries and is also becoming a serious heal...
In atherosclerosis, the accumulation of apolipoprotein B-lipoproteins in the matrix beneath the endo...
Subendothelial macrophages are a major cellularcomponent of atherosclerotic lesions. In response tos...
Atherosclerosis is still one of the main causes of death around the globe. This condition leads to v...
Cardiovascular disease, a leading cause of mortality in developed countries, is mainly caused by ath...
Inflammatory monocytes and macrophages are innate im-mune cells that promote the growth and complica...
<p>Monocytes differentiate into macrophages which endocytose ox-LDL and become foam cells. SMCs are ...
In the development of atherosclerotic lesions, three basic processes occur: 1) invasion of the arter...
<p>LDL and HDL are oxidized by free radicals, and become ox-LDL and ox-HDL respectively. Ox-LDL recr...
Atherosclerosis can be regarded as chronic inflammatory disease driven by lipid accumulation in the ...
Human monocytes are known to be multifunctional cells that combine a variety of functions, including...
Cardiovascular disease is the biggest killer globally and the principal contributing factor to the p...
Atherosclerosis is a chronic inflammatory disease occurring within the artery wall and is an underly...
Multi-ligand, cell surface receptors for modified lipoproteins are called scavenger receptors. They ...