A novel dimerization of 1-hydroxyindoles

金沢大学大学院自然科学研究科生理活性物質科学金沢大学薬学部1-Hydroxyindoles are sensitive to acids and undergo four types of competing reactions; dehydroxylation, nucleophilic substitution, dimerization, and formation of hexacyclic dimer. The direction of the reaction seems to be determined depending on the subtle balance of substrate structures, acids, and reaction conditions. Stuctures of variety of products are unequivocally determined by X-ray single crystallographic analyses and chemical correlations