We study the impact of parameter uncertainty in multiperiod portfolio selection with trading costs. We analytically characterize the expected loss of a multiperiod investor, and we find that it is equal to the product of two terms. The first term corresponds with the single-period utility loss in the absence of transaction costs, as characterized by Kan and Zhou (2007), whereas the second term captures the multiperiod effects on the overall utility loss. To mitigate the impact of parameter uncertainty, we propose two multiperiod shrinkage portfolios. The first multiperiod shrinkage portfolio combines the Markowitz portfolio with a target portfolio. This method diversifies the effects of parameter uncertainty and reduces the risk of ...