Human cytomegalovirus (HCMV) infection induces persistent changes in the host immune system, namely a sustained expansion of effector memory and cytotoxic specific T lymphocytes, the production of antibodies (Ab) and, in some individuals, associates with the differentiation of a functionally competent Natural Killer (NK) cell subset with adaptive features, identified by the elevated expression of the activating receptor CD94/NKG2C. NK cells are considered important players in the defence against HCMV, yet the exact mechanisms by which these cells contribute to primary infection and viral reactivation control remain partially understood. In the present study, we have characterized three distinct mechanisms by which NK cells could participate...
Development of an effective vaccine against human cytomegalovirus (HCMV) is a need of utmost medical...
Altres ajuts: We thank Dr. Carsten Kirschning for generously providing the blocking mAb anti-TLR2 an...
We comparatively analyzed the natural killer (NK) cell response against HCMV-infected pro-inflammato...
Human cytomegalovirus (HCMV) infection induces persistent changes in the host immune system, namely ...
Natural killer (NK) cells play a dual role in the defense against viral pathogens by directly lysing...
Human cytomegalovirus (HCMV) infection induces a persistent reconfiguration of the NK cell compartm...
Human cytomegalovirus (HCMV) infection exerts broad effects on the immune system. These include the ...
Natural killer (NK) cells play a dual role in the defense against viral pathogens by directly lysing...
Control of human cytomegalovirus (HCMV) requires a continuous immune surveillance, thus HCMV is the ...
El citomegalovirus humano (HCMV) promueve una redistribución del compartimento de células Natural Ki...
Natural killer (NK) cells play an important role in the defense against viral infections. Activation...
Natural killer (NK) cells play a dual role in the defense against viral pathogens by directly lysing...
Human cytomegalovirus (HCMV) infection promotes the differentiation and persistent expansion of a ma...
Immune responses of Natural Killer (NK) cell are controlled by the balance between activating and in...
Anti-viral T cells are thought to regulate whether hepatitis C virus (HCV) and HIV infections result...
Development of an effective vaccine against human cytomegalovirus (HCMV) is a need of utmost medical...
Altres ajuts: We thank Dr. Carsten Kirschning for generously providing the blocking mAb anti-TLR2 an...
We comparatively analyzed the natural killer (NK) cell response against HCMV-infected pro-inflammato...
Human cytomegalovirus (HCMV) infection induces persistent changes in the host immune system, namely ...
Natural killer (NK) cells play a dual role in the defense against viral pathogens by directly lysing...
Human cytomegalovirus (HCMV) infection induces a persistent reconfiguration of the NK cell compartm...
Human cytomegalovirus (HCMV) infection exerts broad effects on the immune system. These include the ...
Natural killer (NK) cells play a dual role in the defense against viral pathogens by directly lysing...
Control of human cytomegalovirus (HCMV) requires a continuous immune surveillance, thus HCMV is the ...
El citomegalovirus humano (HCMV) promueve una redistribución del compartimento de células Natural Ki...
Natural killer (NK) cells play an important role in the defense against viral infections. Activation...
Natural killer (NK) cells play a dual role in the defense against viral pathogens by directly lysing...
Human cytomegalovirus (HCMV) infection promotes the differentiation and persistent expansion of a ma...
Immune responses of Natural Killer (NK) cell are controlled by the balance between activating and in...
Anti-viral T cells are thought to regulate whether hepatitis C virus (HCV) and HIV infections result...
Development of an effective vaccine against human cytomegalovirus (HCMV) is a need of utmost medical...
Altres ajuts: We thank Dr. Carsten Kirschning for generously providing the blocking mAb anti-TLR2 an...
We comparatively analyzed the natural killer (NK) cell response against HCMV-infected pro-inflammato...