textHerein is described our synthetic studies towards the synthesis of secu'amamine A, a member of the Securinega alkaloids. The first chapter describes the isolation, biological significance and previous synthesis of secu'amamine A. Chapter 2 discusses our proposed biogenetic origin of secu'amamine A from allosecurinine and the model studies to support the intermediacy of the putative aziridinium ion. Chapter 3 discusses our synthetic approach to the formation of rings A and C, as well as investigations on the regioselective functionalization of 1,2-dihydropyridines. Chapter 4 discusses the synthesis of ring D from ring D' and the transformations of our advanced intermediates with different carbamate protective groups. Chapter 5 consists o...
Throughout history, organisms have ensured their survival by producing a wide variety of small molec...
The planning and implementation of an enantioselective total synthesis of (+)-scholarisine A is pres...
Securinega alkaloids are indolizidine alkaloids extracted from the leaf and root of an Asian plant, ...
The Securinega alkaloids feature a compact tetracyclic structural framework and can be divided into ...
The synthesis of the Securinega alkaloid secu’amamine E (ent–virosine A) has been accomplished for t...
Chapter 1 presents a flexible synthesis of (-)-securinine in 18 steps and 16% overall isolated yield...
Abstract: The Securinega alkaloids are a family of approximately 20 tetracyclic compounds isolated f...
The synthesis of the <i>Securinega</i> alkaloid secu’amamine E (<i>ent</i>-virosine A) has been acco...
From \(Securinega\) \(suffruticosa\) (Pall.) Rehd (Fam. Euphorbiaceae), grown in Rongo, North Bengal...
This dissertation is divided into two projects concerning natural product synthesis and methodology ...
The asymmetric total synthesis of (−)-14,15-dihydrosecurinine and the formal total synthesis of (−)-...
Part A of this thesis provides a resume1 of the synthesis of various radioactively labelled forms of...
This thesis describes the development of a novel synthetic route towards the Securinega alkaloids, s...
© 2020 Wiley-VCH Verlag GmbH & Co. KGaA, WeinheimPresented here is a concise synthesis of secu′amami...
The isolation of flueggenines A and B by Yue and co-workers in 2006 has triggered a burst of isolati...
Throughout history, organisms have ensured their survival by producing a wide variety of small molec...
The planning and implementation of an enantioselective total synthesis of (+)-scholarisine A is pres...
Securinega alkaloids are indolizidine alkaloids extracted from the leaf and root of an Asian plant, ...
The Securinega alkaloids feature a compact tetracyclic structural framework and can be divided into ...
The synthesis of the Securinega alkaloid secu’amamine E (ent–virosine A) has been accomplished for t...
Chapter 1 presents a flexible synthesis of (-)-securinine in 18 steps and 16% overall isolated yield...
Abstract: The Securinega alkaloids are a family of approximately 20 tetracyclic compounds isolated f...
The synthesis of the <i>Securinega</i> alkaloid secu’amamine E (<i>ent</i>-virosine A) has been acco...
From \(Securinega\) \(suffruticosa\) (Pall.) Rehd (Fam. Euphorbiaceae), grown in Rongo, North Bengal...
This dissertation is divided into two projects concerning natural product synthesis and methodology ...
The asymmetric total synthesis of (−)-14,15-dihydrosecurinine and the formal total synthesis of (−)-...
Part A of this thesis provides a resume1 of the synthesis of various radioactively labelled forms of...
This thesis describes the development of a novel synthetic route towards the Securinega alkaloids, s...
© 2020 Wiley-VCH Verlag GmbH & Co. KGaA, WeinheimPresented here is a concise synthesis of secu′amami...
The isolation of flueggenines A and B by Yue and co-workers in 2006 has triggered a burst of isolati...
Throughout history, organisms have ensured their survival by producing a wide variety of small molec...
The planning and implementation of an enantioselective total synthesis of (+)-scholarisine A is pres...
Securinega alkaloids are indolizidine alkaloids extracted from the leaf and root of an Asian plant, ...