A new and efficient method has been developed for the quantitative transformation of chalcon.es to pyrimidine frame work via solid support catalysis. Silica supported sulphuric acid (SSA) efficiently catalyzed the reaction of a-[3-unsaturated carbonyl, chalcones (1-10) with urea to afford substituted pyrimidin-2(1H)-ones (11-20) in good to excellent yield. The interesting behaviour of SSA lies in the fact that it can be re-used after simple washing with chloroform thereby rendering this procedure more economical. The chemical structures were confrrmed by analytical data as well as spectroscopic mean
A series of some new pyrimidine containing sulfonamides moieties were synthesized via the reaction o...
The majority of the drugs on the market today are entirely chemically synthesized in the laboratory....
A simple, green and efficient solventless procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)...
There are two series of α, β-unsaturated ketones derived form Biphenyl and 9H-Fluorenyl, and ketones...
An efficient method for the synthesis of 4,6-diarylpyrimidin-2(1H)-ones or thiones by using SiO2.CAA...
Claisen first synthesized Chalcone in 1881 by condensing acetophenone with benzaldehyde using sodium...
AbstractThe work involves synthesis of novel Schiff base derivatives containing a pyrimidine unit st...
<div><p></p><p>Straightforward procedures for the fast and efficient synthesis of differently substi...
We report an efficient silica-H2SO4 mediated synthesis of a variety of chalcones that afforded the t...
The majority of the drugs on the market today are entirely chemically synthesized in the laboratory....
Recent study on chalcone derivatives has attracted much attention due to its great interest in phar...
Chalcones are a type of molecule that can be considered as easily synthesizable through aldol conden...
Pyrimidine-2-one derivatives, 2-[2-{1ʹ-(p-nitrophenyl)-6ʹ-(substituted-phenyl)-pyrimidine-2ʹ-one-4ʹ-...
2-substituted derivatives of indane-1,3-diones have shown many activities. Chalcones possess a numb...
1 SUMMARY This dissertation thesis deals with searching for potential drugs, particularly with prepa...
A series of some new pyrimidine containing sulfonamides moieties were synthesized via the reaction o...
The majority of the drugs on the market today are entirely chemically synthesized in the laboratory....
A simple, green and efficient solventless procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)...
There are two series of α, β-unsaturated ketones derived form Biphenyl and 9H-Fluorenyl, and ketones...
An efficient method for the synthesis of 4,6-diarylpyrimidin-2(1H)-ones or thiones by using SiO2.CAA...
Claisen first synthesized Chalcone in 1881 by condensing acetophenone with benzaldehyde using sodium...
AbstractThe work involves synthesis of novel Schiff base derivatives containing a pyrimidine unit st...
<div><p></p><p>Straightforward procedures for the fast and efficient synthesis of differently substi...
We report an efficient silica-H2SO4 mediated synthesis of a variety of chalcones that afforded the t...
The majority of the drugs on the market today are entirely chemically synthesized in the laboratory....
Recent study on chalcone derivatives has attracted much attention due to its great interest in phar...
Chalcones are a type of molecule that can be considered as easily synthesizable through aldol conden...
Pyrimidine-2-one derivatives, 2-[2-{1ʹ-(p-nitrophenyl)-6ʹ-(substituted-phenyl)-pyrimidine-2ʹ-one-4ʹ-...
2-substituted derivatives of indane-1,3-diones have shown many activities. Chalcones possess a numb...
1 SUMMARY This dissertation thesis deals with searching for potential drugs, particularly with prepa...
A series of some new pyrimidine containing sulfonamides moieties were synthesized via the reaction o...
The majority of the drugs on the market today are entirely chemically synthesized in the laboratory....
A simple, green and efficient solventless procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)...