International audienceThe new generation of Simpop models presented in this book, as well as the approach followed all along their construction and evaluation, has specifically targeted and tackled the equifinality challenge of (urban) modelling. It is presented as a progression from solving elementary generative problems to adapting models for encompassing a variety of urban situations by sharing open tools.The first chapter presents our empirical knowledge of systems of cities, and ways of summarizing their regular properties. It builds the ‘system of reference’ upon which model-building can take place. Indeed, by generalizing processes and structural properties of empirical case studies in different spatio-temporal contexts, it specifies...