P2AR.10 - Multi-analyte electrochemical biosensors on flexible foils

Enzyme-based electrodes represent an important class of biosensors that allow to electrochemically measure the products derived from a target analyte transformation. Enzymatic electrochemical biosensors, capable to detect glucose and lactate, find application in monitoring diseases, such as diabetes. This work is focused onto the development of an amperometric multy-analyte (glucose and lactate) biosensor based on glucose and lactate oxidase immobilization, loaded into photo-patternable hydrogels. The photo-definable hydrogels act as excellent biocompatible matrices providing near-physiological conditions that minimize protein denaturation. This methodology also allows biosensor miniaturization for a continuous non-invasive glucose/lactate monitoring