Add to ORKGThis project explored using dermal fibroblast-derived extracellular matrices (ECMs) to recapitulate the keratinocyte microenvironmental niche in vitro. The data indicated that fibroblast-derived matrices better supported keratinocytes expansion than substrates of type I collagen. ECM composition was found to profoundly alter the gene expression profiles of keratinocytes grown on these matrices, in that foetal matrices triggered expression of cell cycle genes, whereas adult matrices triggered the expression of a balance of differentiation and cell cycle genes
Background: There is little information on specific interactions between dermal fibroblasts and epid...
Oral keratinocyte behaviour were analysed in two and three dimensional cultures of an immortalised h...
The human epidermis is constantly being renewed. Post mitotic terminally differentiated cells are sh...
The long-term expansion of keratinocytes under serum- and feeder free conditions generally results i...
Includes abstract.Includes bibliographical references (leaves 122-157).Stromal cells and the extrace...
There are multiple fibroblast populations found in adult skin dermis. Within this thesis I will dis...
Skin is one of the most accessible tissues for experimental biomedical sciences, and cultured skin c...
Extracellular matrices (ECMs) play an important rote as components of basement membrane of normal hu...
Culture microenvironment plays a critical role in the propagation and differentiation of human embry...
The corneal wound healing process is a complex process, which often leads to the development of scar...
Background: Autologous keratincoytes are routinely expanded using irradiated mouse fibroblasts and b...
The corneal wound healing process is a complex process, which often leads to the development of scar...
The extracellular matrix (ECM) is a specialised scaffold as well as a biochemical signalling platfor...
The extracellular matrix (ECM) is a specialised scaffold as well as a biochemical signalling platfor...
BACKGROUND: While several commercial dermo-epidermal scaffolds can promote wound healing of the ...
Background: There is little information on specific interactions between dermal fibroblasts and epid...
Oral keratinocyte behaviour were analysed in two and three dimensional cultures of an immortalised h...
The human epidermis is constantly being renewed. Post mitotic terminally differentiated cells are sh...
The long-term expansion of keratinocytes under serum- and feeder free conditions generally results i...
Includes abstract.Includes bibliographical references (leaves 122-157).Stromal cells and the extrace...
There are multiple fibroblast populations found in adult skin dermis. Within this thesis I will dis...
Skin is one of the most accessible tissues for experimental biomedical sciences, and cultured skin c...
Extracellular matrices (ECMs) play an important rote as components of basement membrane of normal hu...
Culture microenvironment plays a critical role in the propagation and differentiation of human embry...
The corneal wound healing process is a complex process, which often leads to the development of scar...
Background: Autologous keratincoytes are routinely expanded using irradiated mouse fibroblasts and b...
The corneal wound healing process is a complex process, which often leads to the development of scar...
The extracellular matrix (ECM) is a specialised scaffold as well as a biochemical signalling platfor...
The extracellular matrix (ECM) is a specialised scaffold as well as a biochemical signalling platfor...
BACKGROUND: While several commercial dermo-epidermal scaffolds can promote wound healing of the ...
Background: There is little information on specific interactions between dermal fibroblasts and epid...
Oral keratinocyte behaviour were analysed in two and three dimensional cultures of an immortalised h...
The human epidermis is constantly being renewed. Post mitotic terminally differentiated cells are sh...