Pancreatic cancer has one of the worst prognoses among all cancers due to the late manifestation of identifiable symptoms and high resistance to chemo- and radiation therapies. In recent years, a cancer development phase termed epithelial-mesenchymal transition (EMT) has gained increasing research focus. The process is implicated in tumour metastasis, and emerging evidence suggests EMT also contributes or induces chemoresistance in several cancers. Nevertheless, the applicability of therapeutic targeting of EMT faces many challenges. In this mini-review, we summarise the evidence supporting the role of EMT in pancreatic cancer progression, focusing particularly on its association with chemoresistance
Epithelial–mesenchymal transition (EMT) is known to play an important role in cancer progression, me...
Pancreatic cancer (PC) is the third leading cause of adult cancer mortality in the United States. Th...
Metastasis is the spread of cancer cells from the primary tumour to distant sites and organs through...
Pancreatic adenocarcinoma (PDAC) is one of the most lethal human malignancies, with median survival ...
Pancreatic adenocarcinoma (PDAC) is one of the most lethal human malignancies, with median survival ...
Pancreatic cancer is a leading cause of cancer related death due to its invasive nature. Despite the...
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies, characterized by aggre...
Globally, pancreatic ductal adenocarcinoma remains among the most aggressive forms of neoplastic dis...
Pancreatic ductal adenocarcinoma (PDAC) ranks as the fourth commonest cause of cancer death while it...
Pancreatic cancer (PC) is the third leading cause of adult cancer mortality in the United States. Th...
Pancreatic ductal adenocarcinoma (PDAC) ranks as the fourth commonest cause of cancer death while it...
Metastasis, tumor progression, and chemoresistance are the major causes of death in patients with pa...
The epithelial-mesenchymal transition (EMT) has a significant role in embryogenesis. EMT is also imp...
Pancreatic ductal adenocarcinoma (PDAC) is one of the malignancies with the worst prognosis despite ...
Epithelial–mesenchymal transition (EMT) is known to play an important role in cancer progression, me...
Epithelial–mesenchymal transition (EMT) is known to play an important role in cancer progression, me...
Pancreatic cancer (PC) is the third leading cause of adult cancer mortality in the United States. Th...
Metastasis is the spread of cancer cells from the primary tumour to distant sites and organs through...
Pancreatic adenocarcinoma (PDAC) is one of the most lethal human malignancies, with median survival ...
Pancreatic adenocarcinoma (PDAC) is one of the most lethal human malignancies, with median survival ...
Pancreatic cancer is a leading cause of cancer related death due to its invasive nature. Despite the...
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies, characterized by aggre...
Globally, pancreatic ductal adenocarcinoma remains among the most aggressive forms of neoplastic dis...
Pancreatic ductal adenocarcinoma (PDAC) ranks as the fourth commonest cause of cancer death while it...
Pancreatic cancer (PC) is the third leading cause of adult cancer mortality in the United States. Th...
Pancreatic ductal adenocarcinoma (PDAC) ranks as the fourth commonest cause of cancer death while it...
Metastasis, tumor progression, and chemoresistance are the major causes of death in patients with pa...
The epithelial-mesenchymal transition (EMT) has a significant role in embryogenesis. EMT is also imp...
Pancreatic ductal adenocarcinoma (PDAC) is one of the malignancies with the worst prognosis despite ...
Epithelial–mesenchymal transition (EMT) is known to play an important role in cancer progression, me...
Epithelial–mesenchymal transition (EMT) is known to play an important role in cancer progression, me...
Pancreatic cancer (PC) is the third leading cause of adult cancer mortality in the United States. Th...
Metastasis is the spread of cancer cells from the primary tumour to distant sites and organs through...