Amongst HIV patients with successful virological responses to antiretroviral therapy (ART), poor CD4+ T-cell recovery is associated with low nadir CD4+ T-cell counts and persistent immune activation. These factors might be influenced by dendritic cell (DC) function. Interferon-a-producing plasmacytoid DC and IL-12-producing myeloid DC were quantified by flow cytometry after stimulation with agonists to TLR7/8 (CL075) or TLR9 (CpG-ODN). These were compared between patients who achieved CD4+ T-cell counts above or below 200 cells/µL after 6months on ART (High vs. Low groups). High Group patients had more DC producing interferon-a or IL-12 at Weeks 6 and 12 on ART than Low Group patients. The frequencies of cytokine-producing DC at Week 12 wer...
HIV infection is characterized by ineffective anti-viral T-cell responses and impaired dendritic cel...
Plasmacytoid dendritic cells (pDCs) are important in innate and adaptive immune responses against vi...
International audienceDendritic cells (DCs) are crucial in adaptive immunity because they are the on...
Amongst HIV patients with successful virological responses to antiretroviral therapy (ART), poor CD4...
Some HIV patients who previously experienced severe immunodeficiency retain low pathogen-specific T-...
Dendritic cell (DC) numbers and functions can be affected by HIV and HCV disease, but the effects of...
Objective: To explore monocyte and dendritic cell immune responses, and their association with futur...
Myeloid and plasmacytoid dendritic cells (DCs) are important mediators of both innate and adaptive i...
Myeloid and plasmacytoid dendritic cells (DCs) are important mediators of both innate and adaptive i...
We previously demonstrated that GM-CSF/IFN- combination allowed the differentiation of monocytes fr...
Plasmacytoid dendritic cells (pDCs) are innate immune cells able to produce large quantities of type...
Abstract: Maturation of dendritic cells (DC) to enhance their capacity to activate T cell immunity t...
In HIV-1 infection, plasmacytoid dendritic cell (PDC) numbers and function are decreased. No detaile...
The function of plasmacytoid dendritic cells (PDC) in chronic human immunodeficiency virus type 1 (H...
This study aimed to evaluate the effects of antiretroviral therapy on plasmacytoid (pDC) and myeloid...
HIV infection is characterized by ineffective anti-viral T-cell responses and impaired dendritic cel...
Plasmacytoid dendritic cells (pDCs) are important in innate and adaptive immune responses against vi...
International audienceDendritic cells (DCs) are crucial in adaptive immunity because they are the on...
Amongst HIV patients with successful virological responses to antiretroviral therapy (ART), poor CD4...
Some HIV patients who previously experienced severe immunodeficiency retain low pathogen-specific T-...
Dendritic cell (DC) numbers and functions can be affected by HIV and HCV disease, but the effects of...
Objective: To explore monocyte and dendritic cell immune responses, and their association with futur...
Myeloid and plasmacytoid dendritic cells (DCs) are important mediators of both innate and adaptive i...
Myeloid and plasmacytoid dendritic cells (DCs) are important mediators of both innate and adaptive i...
We previously demonstrated that GM-CSF/IFN- combination allowed the differentiation of monocytes fr...
Plasmacytoid dendritic cells (pDCs) are innate immune cells able to produce large quantities of type...
Abstract: Maturation of dendritic cells (DC) to enhance their capacity to activate T cell immunity t...
In HIV-1 infection, plasmacytoid dendritic cell (PDC) numbers and function are decreased. No detaile...
The function of plasmacytoid dendritic cells (PDC) in chronic human immunodeficiency virus type 1 (H...
This study aimed to evaluate the effects of antiretroviral therapy on plasmacytoid (pDC) and myeloid...
HIV infection is characterized by ineffective anti-viral T-cell responses and impaired dendritic cel...
Plasmacytoid dendritic cells (pDCs) are important in innate and adaptive immune responses against vi...
International audienceDendritic cells (DCs) are crucial in adaptive immunity because they are the on...