Incorporation of liposomes containing squid tunic ACE-inhibitory peptides into fish gelatin
- Mosquera, Mauricio
- Giménez, Begoña
- Montero García, Pilar
- Gómez Guillén, M. C.
DOIAbstract
[Background]: Hydrolysates from collagen of jumbo squid (Dosidicus gigas) tunics have shown excellent angiotensin I-converting enzyme (ACE)-inhibitory activity. However, peptides directly included in food systems may suffer a decrease in activity, which could be minimized by loading them into nanoliposomes. [Results]: A fraction of peptides with molecular weights <1 kDa obtained from hydrolyzed squid tunics, with reasonably high ACE-inhibitory activity (half-maximal inhibitory concentration IC = 0.096 g L), was encapsulated in phosphatidylcholine nanoliposomes. The peptide concentration affected the encapsulation efficiency and the stability of the resulting liposomes, which remained with a high zeta potential value (-54.3 mV) for at least ...
Add to ORKG