In biological systems, pathways define complex interaction networks where multiple molecular elements are involved in a series of controlled reactions producing responses to specific biomolecular signals. These biosystems are dynamic and there is a need for mathematical and computational methods able to analyze the symbolic elements and the interactions between them and produce adequate readouts of such systems. In this work, we use rewriting logic to analyze the cellular signaling of epidermal growth factor (EGF) and its cell surface receptor (EGFR) in order to induce cellular proliferation. Signaling is initiated by binding the ligand protein EGF to the membrane-bound receptor EGFR so as to trigger a reactions path which have several link...
The molecular causes by which the epidermal growth factor receptor tyrosine kinase induces malignant...
The molecular causes by which the epidermal growth factor receptor tyrosine kinase induces malignant...
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulat...
[EN] In biological systems, pathways define complex interaction networks where multiple molecular el...
Pathway Logic is an approach to modeling cellular processes based on rewriting logic, a simple logic...
The complexity of networks of biological signalling pathways is such that the development of simpli...
AbstractOver the last decade, epidermal growth factor (EGF) signaling has been used repeatedly as a ...
Many approaches to anticancer treatment have had a limited success. A fundamental hurdle to cancer ...
The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor ...
Over the last decade, epidermal growth factor (EGF) signaling has been used repeatedly as a testbed ...
Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2015.Cata...
BACKGROUND: The epidermal growth factor receptor (EGFR) signaling pathway plays a key role in regula...
The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor ...
The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor ...
BACKGROUND: The Epidermal Growth Factor Receptor (EGFR) activated Extracellular-signal Regulated Kin...
The molecular causes by which the epidermal growth factor receptor tyrosine kinase induces malignant...
The molecular causes by which the epidermal growth factor receptor tyrosine kinase induces malignant...
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulat...
[EN] In biological systems, pathways define complex interaction networks where multiple molecular el...
Pathway Logic is an approach to modeling cellular processes based on rewriting logic, a simple logic...
The complexity of networks of biological signalling pathways is such that the development of simpli...
AbstractOver the last decade, epidermal growth factor (EGF) signaling has been used repeatedly as a ...
Many approaches to anticancer treatment have had a limited success. A fundamental hurdle to cancer ...
The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor ...
Over the last decade, epidermal growth factor (EGF) signaling has been used repeatedly as a testbed ...
Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2015.Cata...
BACKGROUND: The epidermal growth factor receptor (EGFR) signaling pathway plays a key role in regula...
The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor ...
The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor ...
BACKGROUND: The Epidermal Growth Factor Receptor (EGFR) activated Extracellular-signal Regulated Kin...
The molecular causes by which the epidermal growth factor receptor tyrosine kinase induces malignant...
The molecular causes by which the epidermal growth factor receptor tyrosine kinase induces malignant...
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulat...