Fluid-structure interaction analysis of venous valve hemodynamics

Venous valves play an important role in ensuring that blood returns to the heart. Nevertheless there are few quantitative reports of venous valve function. This study reports results from a 3D fluid-structure interaction model of a venous valve, including the valve sinus, for varying Reynolds number. Analysis of valve orifice deformation, trans-valvular pressure drop and velocity increase through the valve demonstrate the influence of changes in venous flow on valve geometry and the variation in pressure drop with flow rate. These results inform understanding of the role of venous valves in disease processes and their contribution to circulatory haemodynamics