Quantitative short-wave infrared multispectral imaging of in vivo tissue optical properties
- Wilson, Robert H.
- Nadeau, Kyle P.
- Jaworski, Frank B.
- Rowland, Rebecca
- Nguyen, John Q.
- Crouzet, Christian
- Saager, Rolf B.
- Choi, Bernard
- Tromberg, Bruce J.
- Durkin, Anthony J.
DOIAbstract
Extending the wavelength range of spatial frequency domain imaging (SFDI) into the short-wave infrared (SWIR) has the potential to provide enhanced sensitivity to chromophores such as water and lipids that have prominent absorption features in the SWIR region. Here, we present, for the first time, a method combining SFDI with unstructured (zero spatial frequency) illumination to extract tissue absorption and scattering properties over a wavelength range (850 to 1800 nm) largely unexplored by previous tissue optics techniques. To obtain images over this wavelength range, we employ a SWIR camera in conjunction with an SFDI system. We use SFDI to obtai
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