Nature uses a complex genotype-phenotype map to advance a relatively simple genotype space variational topology to an extremely complex phenotypic variational topology. This dissertation introduces a modular, fixed non-trivial, multi-layered genotype-phenotype map, incorporating an interpretation of the biological processes of transcription and translation into the representation of a Genetic Algorithm (GA), thereby introducing a more flexible phenotypic structure and increasing connectivity. A series of experiments are conducted to examine the impact of the representation on variation and variability, with results indicating that through the inclusion of the proposed multi-layered mapping, only a small fraction of genotypic mutations are...
International audienceThe potential for evolutionary change is deeply anchored in the kind and amoun...
By "phenotypic plasticity" we refer to the capacity of a genotype to exhibit different phenotypes, w...
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the n...
In nature, living organisms can be viewed as the product of their genotype-phenotype mapping (GP-map...
In this paper we investigate the introduction of a multiple-layer genotype-phenotype mapping to a Ge...
By adopting a basic interpretation of the biological processes of transcription and translation, the...
This paper examines the implicit maintenance of diversity within a population through the inclusion ...
Abstract A novel evolutionary method that allows us to study the emergence of modularity for genotyp...
The identification of mechanisms by which constraints on phenotypic variability are tuned in nature...
Systems biology is accumulating a wealth of understanding about the structure of genetic regulatory ...
This paper examines the use of the biological concepts of transcription and translation, to introduc...
One of the most fundamental and least understood elements of evolution is the mapping between genoty...
The map between genotype and phenotype is fundamental to biology. Biological information is stored a...
This paper examines the introduction of neutrality as proposed by Kimura (Kimura, 1968) into the gen...
Among the most fundamental features shared by all organisms is the mapping of information encoded in...
International audienceThe potential for evolutionary change is deeply anchored in the kind and amoun...
By "phenotypic plasticity" we refer to the capacity of a genotype to exhibit different phenotypes, w...
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the n...
In nature, living organisms can be viewed as the product of their genotype-phenotype mapping (GP-map...
In this paper we investigate the introduction of a multiple-layer genotype-phenotype mapping to a Ge...
By adopting a basic interpretation of the biological processes of transcription and translation, the...
This paper examines the implicit maintenance of diversity within a population through the inclusion ...
Abstract A novel evolutionary method that allows us to study the emergence of modularity for genotyp...
The identification of mechanisms by which constraints on phenotypic variability are tuned in nature...
Systems biology is accumulating a wealth of understanding about the structure of genetic regulatory ...
This paper examines the use of the biological concepts of transcription and translation, to introduc...
One of the most fundamental and least understood elements of evolution is the mapping between genoty...
The map between genotype and phenotype is fundamental to biology. Biological information is stored a...
This paper examines the introduction of neutrality as proposed by Kimura (Kimura, 1968) into the gen...
Among the most fundamental features shared by all organisms is the mapping of information encoded in...
International audienceThe potential for evolutionary change is deeply anchored in the kind and amoun...
By "phenotypic plasticity" we refer to the capacity of a genotype to exhibit different phenotypes, w...
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is arguably the n...