Add to ORKGThe synthesis of three macrotriazoles that are analogues of migrastatin is reported. The synthesis is based on copper(I)- and ruthenium-catalyzed azide-alkyne cycloaddition reactions. The enantiopure terminal alkyne derivatives were prepared by using the Trost desymmetrization, Brown alkoxy-allylation and an efficient Colvin reaction. Biological evaluation of the products revealed a promising efficiency in reducing the ability of MDA-MB-361 cell lines to migrate
The synthesis of the macrolactone core of migrastatin 2, its potent anti-metastasis analogue 34, and...
The 5-amino-1,2,3-triazole-4-carboxylic acid is a suitable molecule for the preparation of collectio...
It is herein described the preparation and evaluation of antimetastatic activity of twenty-six cinna...
The synthesis of three macrotriazoles that are analogues of migrastatin is reported. The synthesis i...
The synthesis of three macrotriazoles that are analogues of migrastatin is reported. The synthesis i...
Migrastatin and isomigrastatin analogues have been synthesised in order to contribute to structure-a...
Journal articleMigrastatin and isomigrastatin analogues have been synthesised in order to contribute...
An efficient and scalable synthesis of a key acyclic intermediate used for the preparation of migras...
An efficient and scalable synthesis of a key acyclic intermediate used for the preparation of migras...
The 5-amino-1,2,3-triazole-4-carboxylic acid is a suitable molecule for the preparation of collectio...
The synthesis of the macrolactone core of migrastatin 2, its potent anti-metastasis analogue 34, and...
O capítulo 1 relata as sínteses da macrolactona da migrastatina 11 e da macrolactona análoga 62a. A ...
Synthesis of macrocylic enones starting from alkyl ether and triazole as a linker was achieved using...
InhA, the enoyl reductase from the mycobacterial type II fatty acid biosynthesis pathway, is a targe...
Abstract Novel 16-triazoles in the 13α-estrone series were synthesized via Cu(I)-catalyzed azide–alk...
The synthesis of the macrolactone core of migrastatin 2, its potent anti-metastasis analogue 34, and...
The 5-amino-1,2,3-triazole-4-carboxylic acid is a suitable molecule for the preparation of collectio...
It is herein described the preparation and evaluation of antimetastatic activity of twenty-six cinna...
The synthesis of three macrotriazoles that are analogues of migrastatin is reported. The synthesis i...
The synthesis of three macrotriazoles that are analogues of migrastatin is reported. The synthesis i...
Migrastatin and isomigrastatin analogues have been synthesised in order to contribute to structure-a...
Journal articleMigrastatin and isomigrastatin analogues have been synthesised in order to contribute...
An efficient and scalable synthesis of a key acyclic intermediate used for the preparation of migras...
An efficient and scalable synthesis of a key acyclic intermediate used for the preparation of migras...
The 5-amino-1,2,3-triazole-4-carboxylic acid is a suitable molecule for the preparation of collectio...
The synthesis of the macrolactone core of migrastatin 2, its potent anti-metastasis analogue 34, and...
O capítulo 1 relata as sínteses da macrolactona da migrastatina 11 e da macrolactona análoga 62a. A ...
Synthesis of macrocylic enones starting from alkyl ether and triazole as a linker was achieved using...
InhA, the enoyl reductase from the mycobacterial type II fatty acid biosynthesis pathway, is a targe...
Abstract Novel 16-triazoles in the 13α-estrone series were synthesized via Cu(I)-catalyzed azide–alk...
The synthesis of the macrolactone core of migrastatin 2, its potent anti-metastasis analogue 34, and...
The 5-amino-1,2,3-triazole-4-carboxylic acid is a suitable molecule for the preparation of collectio...
It is herein described the preparation and evaluation of antimetastatic activity of twenty-six cinna...