Add to ORKGAbnormal activity of the enzyme PI3K can drive cancer growth, and mutations in a PI3K subunit can sometimes lead to non-cancerous overgrowth. A cancer drug that inhibits PI3K dramatically reduces such overgrowth
Mosaic, activating mutations in PIK3CA, the gene encoding the catalytic p110α subunit of class IA ph...
SummaryPIK3CA is mutated in diverse human cancers, but the functional effects of these mutations hav...
The PI3K/AKT pathway is a key target in oncology where most efforts are focussed on phenotypes such ...
PIK3CA is one of the most commonly mutated genes in solid cancers. PIK3CA mutations are also found i...
PIK3CA is one of the most commonly mutated genes in solid cancers. PIK3CA mutations are also found i...
Genetic activation of the class I PI3K pathway is very common in cancer. This mostly results from on...
Genetic activation of the class I PI3K pathway is very common in cancer. This mostly results from on...
The PIK3CA gene, which encodes the p110α catalytic subunit of PI3 kinase (PI3K), is mutationally act...
Abstract | Evolving studies with several different targeted therapeutic agents are demonstrating tha...
Mosaic, activating mutations in PIK3CA, the gene encoding the catalytic p110α subunit of class IA ph...
SummaryPIK3CA is mutated in diverse human cancers, but the functional effects of these mutations hav...
The PI3K/AKT pathway is a key target in oncology where most efforts are focussed on phenotypes such ...
PIK3CA is one of the most commonly mutated genes in solid cancers. PIK3CA mutations are also found i...
PIK3CA is one of the most commonly mutated genes in solid cancers. PIK3CA mutations are also found i...
Genetic activation of the class I PI3K pathway is very common in cancer. This mostly results from on...
Genetic activation of the class I PI3K pathway is very common in cancer. This mostly results from on...
The PIK3CA gene, which encodes the p110α catalytic subunit of PI3 kinase (PI3K), is mutationally act...
Abstract | Evolving studies with several different targeted therapeutic agents are demonstrating tha...
Mosaic, activating mutations in PIK3CA, the gene encoding the catalytic p110α subunit of class IA ph...
SummaryPIK3CA is mutated in diverse human cancers, but the functional effects of these mutations hav...
The PI3K/AKT pathway is a key target in oncology where most efforts are focussed on phenotypes such ...