Add to ORKGIn this paper we describe a combined in-vitro experimental and mathematical modelling approach to predict in-vivo drug-eluting stent kinetics. We coated stents with a mixture of sirolimus and a novel acrylic-based polymer in two different ratios. Our results indicate differential release kinetics between low and high drug dose formulations. Furthermore, mathematical model simulations of target receptor saturation suggest potential differences in efficacy
Drug-eluting coronary stents have been identified as a promising means of treating in-stent resteno...
Drug-eluting stents are cardiovascular stents able to release a medical drug after implantation. The...
Traditional coronary drug-eluting stents (DES) are made from metal and are coated with a permanent p...
In this paper we describe a combined in-vitro experimental and mathematical modelling approach to p...
In this study, we developed a predictive model of in vivo stent based drug release and distribution ...
Drug-eluting stents have been used widely to prevent restenosis of arteries following percutaneous b...
Although drug-eluting stents (DES) are now widely used for the treatment of coronary heart disease, ...
With the aim of optimizing Drug Eluting Stents (DES), particular attention has been laid on computat...
A mathematical model of a drug-eluting stent is proposed. The model considers a polymer region, cont...
Drug-eluting stents have significantly improved the treatment of coronary artery disease. They offer...
Drug-eluting stents have significantly improved the treatment of coronary artery disease. They offer...
A mathematical model of a drug-eluting stent is proposed. The model considers a polymer region, cont...
Drug-eluting stents have been used widely to prevent restenosis of arteries following percutaneous b...
Drug-eluting stents (DES), which release anti-proliferative drugs into the arterial wall in a contro...
The advent of drug-eluting stents (DES) has revolutionised the treatment of coronary artery disease....
Drug-eluting coronary stents have been identified as a promising means of treating in-stent resteno...
Drug-eluting stents are cardiovascular stents able to release a medical drug after implantation. The...
Traditional coronary drug-eluting stents (DES) are made from metal and are coated with a permanent p...
In this paper we describe a combined in-vitro experimental and mathematical modelling approach to p...
In this study, we developed a predictive model of in vivo stent based drug release and distribution ...
Drug-eluting stents have been used widely to prevent restenosis of arteries following percutaneous b...
Although drug-eluting stents (DES) are now widely used for the treatment of coronary heart disease, ...
With the aim of optimizing Drug Eluting Stents (DES), particular attention has been laid on computat...
A mathematical model of a drug-eluting stent is proposed. The model considers a polymer region, cont...
Drug-eluting stents have significantly improved the treatment of coronary artery disease. They offer...
Drug-eluting stents have significantly improved the treatment of coronary artery disease. They offer...
A mathematical model of a drug-eluting stent is proposed. The model considers a polymer region, cont...
Drug-eluting stents have been used widely to prevent restenosis of arteries following percutaneous b...
Drug-eluting stents (DES), which release anti-proliferative drugs into the arterial wall in a contro...
The advent of drug-eluting stents (DES) has revolutionised the treatment of coronary artery disease....
Drug-eluting coronary stents have been identified as a promising means of treating in-stent resteno...
Drug-eluting stents are cardiovascular stents able to release a medical drug after implantation. The...
Traditional coronary drug-eluting stents (DES) are made from metal and are coated with a permanent p...