In this paper, we introduce two perturbations in the classical deterministic susceptible–infected–susceptible epidemic model. Greenhalgh and Gray [4] in 2011 use a perturbation on β in SIS model. Based on their previous work, we consider another perturbation on the parameter μ+ γ and formulate the original model as a stochastic differential equation (SDE) with two independent Brownian Motions for the number of infected population. We then prove that our Model has a unique and bounded global solution I ( t ) . Also we establish conditions for extinction and persistence of the infected population I ( t ) . Under the conditions of persistence, we show that there is a unique stationary distribution and derive its mean and variance. Computer sim...