Add to ORKGA concise route to the 6-azido-6-deoxy-α-galactosyl-phytosphingosine derivative 9 is reported. Orthogonal protection of the two amino groups allows elaboration of 9 into a range of 6-N-derivatized α-galactosyl ceramides by late-stage introduction of the acyl chain of the ceramide and the 6-N-group in the sugar head-group. Biologically active glycolipids 6 and 8 have been synthesized to illustrate the applicability of the approach
The glycolipid α-galactosyl ceramide, α-GalCer, has been shown to stimulate the proliferation of mur...
Le sujet de thèse concerne l’immunothérapie induite par des glycolipides synthétiques dont le chef ...
AbstractA library of dimeric CD1d ligands, containing two α-galactosyl ceramide (α-GalCer) units lin...
A concise route to the 6-azido-6-deoxy-α-galactosyl-phytosphingosine derivative <b>9</b> is reported...
AbstractWe herein report a faster and less cumbersome synthesis of the biologically attractive, α-ga...
We herein report a faster and less cumbersome synthesis of the biologically attractive, α-galactosyl...
Several L-fucoglycolipids are associated with diseases such as cancer, cystic fibrosis and rheumatoi...
A synthesis strategy for the swift generation of 4"-modified alpha-galactosylceramide (alpha-GalCer)...
Invariant Natural Killer T-cells (iNKT-cells) are an attractive target for immune response modulatio...
Invariant Natural Killer T-cells (iNKT-cells) are an attractive target for immune response modulatio...
Abstractα-Glucosyl ceramides 4 and 5 have been synthesised and evaluated for their ability to stimul...
a-Glucosyl ceramides 4 and 5 have been synthesised and evaluated for their ability to stimulate the ...
AbstractStimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and it...
KRN7000 anti-tumor activity is due to immune system stimulation. It acts on autoimmunes diseases, ba...
AbstractSeveral l-fucoglycolipids are associated with diseases such as cancer, cystic fibrosis and r...
The glycolipid α-galactosyl ceramide, α-GalCer, has been shown to stimulate the proliferation of mur...
Le sujet de thèse concerne l’immunothérapie induite par des glycolipides synthétiques dont le chef ...
AbstractA library of dimeric CD1d ligands, containing two α-galactosyl ceramide (α-GalCer) units lin...
A concise route to the 6-azido-6-deoxy-α-galactosyl-phytosphingosine derivative <b>9</b> is reported...
AbstractWe herein report a faster and less cumbersome synthesis of the biologically attractive, α-ga...
We herein report a faster and less cumbersome synthesis of the biologically attractive, α-galactosyl...
Several L-fucoglycolipids are associated with diseases such as cancer, cystic fibrosis and rheumatoi...
A synthesis strategy for the swift generation of 4"-modified alpha-galactosylceramide (alpha-GalCer)...
Invariant Natural Killer T-cells (iNKT-cells) are an attractive target for immune response modulatio...
Invariant Natural Killer T-cells (iNKT-cells) are an attractive target for immune response modulatio...
Abstractα-Glucosyl ceramides 4 and 5 have been synthesised and evaluated for their ability to stimul...
a-Glucosyl ceramides 4 and 5 have been synthesised and evaluated for their ability to stimulate the ...
AbstractStimulation of iNKT cells by α-galactosyl ceramide (α-GalCer), also known as KRN7000, and it...
KRN7000 anti-tumor activity is due to immune system stimulation. It acts on autoimmunes diseases, ba...
AbstractSeveral l-fucoglycolipids are associated with diseases such as cancer, cystic fibrosis and r...
The glycolipid α-galactosyl ceramide, α-GalCer, has been shown to stimulate the proliferation of mur...
Le sujet de thèse concerne l’immunothérapie induite par des glycolipides synthétiques dont le chef ...
AbstractA library of dimeric CD1d ligands, containing two α-galactosyl ceramide (α-GalCer) units lin...